| Type | Description |
|---|---|
| Definition | transducer of ERBB2, 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:17:00 | LncRNA WEE2-AS1 promotes proliferation and inhibits apoptosis in triple negative breast cancer cells via regulating miR-32-5p/TOB1 axis. | 32307083 |
| 2020-01-11 12:16:00 | The downregulation of DAL-1 and TOB1 expression is associated with shorter survival of gastric cancer patients and may be considered potential novel markers for predicting the outcomes of patients with gastric cancer | 30962003 |
| 2019-11-09 12:19:00 | TOB1 was found to be directly targeted by miR-371a-3p, in which TOB1 was down-regulated by miR-371a-3p in gastric cancer (GC). Most importantly, results showed that TOB1 plays a tumor-suppressive role in GC cells, and it is required for the miR-371a-3p's oncogenic activities in GC cells. | 30529155 |
| 2019-04-27 10:23:00 | Our findings provide important insights into a previously unrecognized oncogenic role of Tob1 in colon cancer and suggest that Tob1 is an adverse prognostic factor and therapeutic target for colon cancer. | 30447686 |
| 2017-10-21 11:20:00 | MiR-590 targets Tob1 that is significantly decreased in patients with multiple sclerosis. | 28947212 |
| Type | IDs |
|---|---|
| Synonymous | APRO5, APRO6, PIG49, TOB, TROB, TROB1 |
| Gene |
UniProtKB-ID:
TOB1_HUMAN
UniprotKB:
P50616
UniParc:
UPI00001370FB
EMBL:
CR536487,
BT019380,
BT019381,
BC031406,
BC070493,
CH471109,
D38305,
CR541686,
AK313904,
BC098415
Ensembl:
ENSG00000141232
KO:
hsa:10140
|
| Nucleutide sequences |
EMBL-CDS:
BAA07423.1,
AAH98415.1,
AAV38188.1,
CAG38726.1,
EAW94578.1,
AAH70493.1,
EAW94577.1,
AAV38187.1,
CAG46487.1,
BAG36627.1,
AAH31406.1
Ensembl_TRS:
ENST00000268957,
ENST00000499247
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000268957,
ENSP00000427695
RefSeq:
NP_001230814.1,
NP_001230806.1,
NP_005740.1
|
| Others |
UniRef100:
UniRef100_P50616
UniRef90:
UniRef90_P50616
UniRef50:
UniRef50_P50616
UniGene:
Hs.703321,
Hs.744946
CCDS:
CCDS11576.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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