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10130 PDIA6

10130

PDIA6

protein disulfide isomerase family A member 6

protein-coding

Homo sapiens

基因描述

Type Description
Definition protein disulfide isomerase family A member 6

研究结论

Date Results Publications
2020-07-04 12:13:00 One novel transcriptome-wide significant association from this study is the downregulation of PDIA6, which showed minimal evidence of association in the genome-wide association study (GWAS). 31230729
2019-08-31 12:08:00 The results of this study suggest that PDIA6 is an important component of EGFR-mediated migration and invasion of U87MG cells. 27540907
2019-08-24 10:04:00 PDIA6 is overexpressed in NSCLC and inhibits cisplatin-induced NSCLC cell apoptosis and autophagy via the MAP4K1/JNK/c-Jun signaling pathway, suggesting that PDIA6 may serve as a biomarker and therapeutic target for NSCLC patients. 30922965
2019-04-20 10:49:00 The cell surface trafficking of PDIA1, PDIA3, and PDIA6 is dependent on KDELR1, which travels in a dynamic manner to the cell surface. This transport is assumed to result in PDI cell surface association, which differs from PDI inducible secretion into the extracellular space. 30958660
2019-04-13 11:01:00 ERp5 triggers fibrinogen dissociation from aIIbb3 integrin. 29932420

名称对应

Type IDs
Synonymous ERP5, P5, TXNDC7
Gene
UniProtKB-ID: PDIA6_HUMAN, A0A384NPU5_HUMAN
UniprotKB: Q15084, A0A384NPU5
UniParc: UPI000013148C, UPI0001914B42, UPI000173A3ED, UPI0000421D0D, UPI000022BCCE
EMBL: U79278, AK127433, BC001312, AK297547, AK289428, GQ891476, D49489, AK294347, AC092687, CH471053, AK131234
Ensembl: ENSG00000143870
KO: hsa:10130
Nucleutide sequences
EMBL-CDS: BAH11740.1, BAA08450.1, EAX00950.1, BAF82117.1, AAY24070.1, AAB50217.1, BAH12614.1, BAC86977.1, AAH01312.1, BAG54757.1, ADO22338.1
Ensembl_TRS: ENST00000404824, ENST00000540494, ENST00000617249, ENST00000404371, ENST00000272227, ENST00000381611
Protein sequencees
Ensembl_PRO: ENSP00000385385, ENSP00000481892, ENSP00000371024, ENSP00000438778, ENSP00000272227, ENSP00000384459
RefSeq: NP_001269635.1, NP_001269633.1, NP_005733.1, XP_011508610.1, NP_001269636.1, NP_001269634.1
Others
UniRef100: UniRef100_Q15084
UniRef90: UniRef90_Q15084
UniRef50: UniRef50_Q15084
UniGene: Hs.212102
CCDS: CCDS62852.1, CCDS62854.1, CCDS1675.1, CCDS62853.1, CCDS62855.1

全选

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