| Type | Description |
|---|---|
| Definition | RAS guanyl releasing protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:12:00 | Dysregulated RASGRP1 expression through RUNX1 mediated transcription promotes autoimmunity. | 33065764 |
| 2021-01-09 13:30:00 | Nurr1 performs its anti-inflammatory function by regulating RasGRP1 expression in neuro-inflammation. | 32612143 |
| 2020-10-24 14:01:00 | RasGRP1 is a potential biomarker to stratify anti-EGFR therapy response in colorectal cancer. | 31237864 |
| 2020-08-15 19:03:00 | Mechanistic Characterization of RASGRP1 Variants Identifies an hnRNP-K-Regulated Transcriptional Enhancer Contributing to SLE Susceptibility. | 31164884 |
| 2020-05-16 12:21:00 | The expression of VEGF, RasGRP1, and AKT phosphorylation was downregulated in HUVECs exposed to high glucose compared with normal glucose, whereas metformin upregulated the RasGRP1-dependent VEGF signaling and ameliorates the impaired angiogenesis caused by high glucose. RasGRP1 is involved in the VEGF-induced angiogenesis and the pro-angiogenesis effects of metformin under hyperglycemia. | 31120617 |
| Type | IDs |
|---|---|
| Synonymous | CALDAG-GEFI, CALDAG-GEFII, RASGRP |
| Gene |
UniProtKB-ID:
GRP1_HUMAN,
B2RA89_HUMAN
UniprotKB:
O95267,
B2RA89
UniParc:
UPI000006FE1C,
UPI0000F53501,
UPI0000F26526,
UPI0000F2653D,
UPI00017506C2,
UPI0000500230
EMBL:
AF081195,
AK314091,
AY966005,
AY634315,
BC067298,
AF106071,
BC109297,
AF081197,
AY858556,
AB208848,
BC109296,
AY954625
Ensembl:
ENSG00000172575
KO:
hsa:10125
|
| Nucleutide sequences |
EMBL-CDS:
AAC97349.1,
AAH67298.1,
AAI09298.1,
AAW32406.2,
AAX54699.4,
BAD92085.1,
AAC79699.1,
AAT47482.2,
AAF21898.1,
AAI09297.1,
AAX76907.1,
BAG36786.1
Ensembl_TRS:
ENST00000310803,
ENST00000414708,
ENST00000450598,
ENST00000559830,
ENST00000558164
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000413105,
ENSP00000454164,
ENSP00000310244,
ENSP00000388540,
ENSP00000452721
RefSeq:
NP_005730.2,
XP_005254171.1,
NP_001122074.1,
XP_011519453.1,
NP_001293015.1,
XP_016877349.1
|
| Others |
UniRef100:
UniRef100_B2RA89,
UniRef100_O95267
UniRef90:
UniRef90_O95267
UniRef50:
UniRef50_O95267
UniGene:
Hs.591127
CCDS:
CCDS45221.1,
CCDS45222.1,
CCDS76733.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员