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10124 ARL4A

10124

ARL4A

ADP ribosylation factor like GTPase 4A

protein-coding

Homo sapiens

基因描述

Type Description
Definition ADP ribosylation factor like GTPase 4A

研究结论

Date Results Publications
2019-06-29 10:55:00 Arl4A participates in Slit2/Robo1 signaling to modulate cell motility by regulating Cdc42 activity. 30427759
2012-04-21 12:02:00 Deletion of the ARL4A-interacting region of GCC185 results in inability to maintain Golgi structure and modulate endosome-to-Golgi transport. 22159419
2011-12-31 12:31:00 membrane targeting of ELMO via Arl4A promotes cytoskeletal reorganization including membrane ruffling and stress fiber disassembly via an ELMO-DOCK1800-Rac signaling pathway. 21930703
2010-01-21 00:00:00 Study shows that three related Arf-like GTPases Arl4a, Arl4c, and Arl4d, are able to recruit ARNO and other cytohesins to the plasma membrane by binding to their PH domains irrespective of whether they are in the diglycine or triglycine form. 17398095
2010-01-21 00:00:00 The loss of PTEN was shown to lead to increased levels of ARF4L protein but no change in transcript levels. The ARF4L transcript preferentially localized to the polysomal compartment after PTEN loss in glioma. 18240926

名称对应

Type IDs
Synonymous ARL4
Gene
UniProtKB-ID: ARL4A_HUMAN, A0A024R9Z2_HUMAN
UniprotKB: P40617, A0A024R9Z2
UniParc: UPI000005273E
EMBL: CH471073, AF493890, BC003027, AK313233, BC001111, U73960, CH236948
Ensembl: ENSG00000122644
KO: hsa:10124
Nucleutide sequences
EMBL-CDS: AAM12604.1, AAB39713.1, EAL24295.1, BAG36044.1, AAH01111.1, AAH03027.1, EAW93650.1, EAW93652.1
Gene_ORFName: hCG_17385
Ensembl_TRS: ENST00000404894, ENST00000396664, ENST00000356797, ENST00000651779, ENST00000396663, ENST00000396662
Protein sequencees
Ensembl_PRO: ENSP00000349250, ENSP00000385236, ENSP00000498350, ENSP00000379897, ENSP00000379899, ENSP00000379898
RefSeq: NP_005729.1, NP_997625.1, NP_001182325.1, NP_001032241.1
Others
UniRef100: UniRef100_P40617
UniRef90: UniRef90_P40617
UniRef50: UniRef50_P40617
UniGene: Hs.245540
CCDS: CCDS5359.1

全选

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研究热度

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