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10113 PREB

10113

PREB

prolactin regulatory element binding

protein-coding

Homo sapiens

基因描述

Type Description
Definition prolactin regulatory element binding

研究结论

Date Results Publications
2019-03-23 12:20:00 Both cTAGE5 and SEC12 were exported with TANGO1 in large COPII carriers. 30545919
2018-12-22 11:55:00 Administration of recombinant adenovirus containing human PREB to db/db, ob/ob, and DIO mice diminished glucose, insulin, and pyruvate tolerance indicating PREB to be a negative regulator of liver gluconeogenic genes. 29601978
2018-03-31 10:36:00 Wls-SEC12 binding is stable, with the interacting interface biochemically mapped to cytosolic segments of individual proteins. Mutant Wls that fails to communicate with the COPII machinery cannot effectively support Wnt secretion. These data suggest that formation of early Wnt secretory vesicles is carefully regulated to ensure proper export of functional ligands 28515233
2016-07-30 11:44:00 These results indicate that PREB locates at the hepatitis C virus replication complex by interacting with NS4B. 26739056
2014-11-22 11:50:00 Sec12, a guanine-nucleotide exchange factor for Sar1 guanosine triphosphatase, is concentrated at endoplasmic reticulum exit sites and that this concentration of Sec12 is specifically required for the secretion of collagen VII but not other proteins. 25202031

名称对应

Type IDs
Synonymous SEC12
Gene
UniProtKB-ID: PREB_HUMAN, Q05DB2_HUMAN, B5MC98_HUMAN
UniprotKB: Q9HCU5, Q05DB2, B5MC98
UniParc: UPI0000073C9D, UPI0000D4DE41, UPI000014DB54
EMBL: BC012890, BC041032, BC002765, AK023064, AF227166, BC016472, AC013403, BC016906, CH471053, AF203687, AF226684
Ensembl: ENSG00000138073
KO: hsa:10113
Nucleutide sequences
EMBL-CDS: EAX00627.1, AAH16472.1, AAF74572.1, AAG01692.1, AAX93170.1, AAH41032.1, BAB14385.1, AAF19192.1, AAH12890.1, AAH02765.1, AAH16906.1, EAX00629.1
Gene_ORFName: hCG_23709
Ensembl_TRS: ENST00000260643, ENST00000406567
Protein sequencees
Ensembl_PRO: ENSP00000260643, ENSP00000384032
RefSeq: NP_001317416.1, NP_001317415.1, NP_001317414.1, NP_037520.1, NP_001317413.1
Others
UniRef100: UniRef100_B5MC98, UniRef100_Q9HCU5
UniRef90: UniRef90_Q9HCU5
UniRef50: UniRef50_Q9HCU5
UniGene: Hs.279784
CCDS: CCDS1738.1

全选

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