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101119678 DLK1

101119678

DLK1

delta like non-canonical Notch ligand 1

protein-coding

Ovis aries

基因描述

Type Description
Definition delta like non-canonical Notch ligand 1

研究结论

Date Results Publications
2016-07-02 10:44:00 Results describe transgenic mice that ectopically express PEG11 in skeletal muscle, and show that they also exhibit a muscular hypertrophy phenotype suggesting that DLK1 as PEG11 act together in causing the muscular hypertrophy of callipyge sheep. 26474044
2015-10-31 11:36:00 DLK-1 expression was significantly (P < 0.01) and positively correlated with IGF-I expression. 25501243
2015-07-11 04:37:00 findings show that the callipyge muscular hypertrophy phenotype correlates with abnormally high DLK1 expression during the postnatal period in the affected sheep and that this elevation is specific to the hypertrophy-responsive fast-twitch muscles 15834634
2015-07-11 04:37:00 The callipyge genotype class did not significantly affect conception rates, fecundity, maternal ability, or ewe longevity. 16424258
2015-07-11 04:37:00 DLK1 expression was upregulated in callipyge animals at both postnatal ages in the semimembranosus, increased DLK1 expression was likely the primary cause of muscle hypertrophy, but a contribution of PEG11 to the phenotype cannot be ruled. 17121598

名称对应

Type IDs
Gene
Nucleutide sequences
Protein sequencees
RefSeq: XP_027813205.1, XP_027813204.1, XP_027813203.1
Others

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