SGK2 - serum/glucocorticoid regulated kinase 2-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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10110 SGK2

基因描述

Type	Description
Definition	serum/glucocorticoid regulated kinase 2

研究结论

Date	Results	Publications
2021-02-06 13:55:00	SGK2 is overexpressed in colon cancer and promotes epithelial-mesenchymal transition in colon cancer cells.	32565024
2020-12-12 13:28:00	Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells.	32848212
2020-08-15 19:06:00	SGK2 promotes renal cancer progression via enhancing ERK 1/2 and AKT phosphorylation.	31002126
2017-07-22 10:30:00	Loss of the paternally derived allele of the imprinted SGK2 gene is associated with Shwachman-Diamond syndrome.	27553422
2017-07-15 10:49:00	These findings suggest that SGK2 promotes hepatocellular carcinoma progression and mediates glycogen synthase kinase 3 beta/beta-catenin signaling in hepatocellular carcinoma cells.	28639896

名称对应

Type	IDs
Synonymous	H-SGK2, dJ138B7.2
Gene	UniProtKB-ID: SGK2_HUMAN UniprotKB: Q9HBY8 UniParc: UPI000002B385, UPI0000033528, UPI0001565472 EMBL: BT020098, Z98752, AF169034, AF186470, BC065511, BC014037, AY987010 Ensembl: ENSG00000101049 KO: hsa:10110
Nucleutide sequences	EMBL-CDS: AAH65511.1, AAF12757.2, AAH14037.3, AAV38901.1, AAX88805.1, AAG17012.1 Ensembl_TRS: ENST00000341458, ENST00000426287, ENST00000423407, ENST00000373100
Protein sequencees	Ensembl_PRO: ENSP00000392795, ENSP00000340608, ENSP00000362192, ENSP00000412214 RefSeq: NP_001186193.1, NP_733794.1, NP_057360.2
Others	UniRef100: UniRef100_Q9HBY8 UniRef90: UniRef90_Q9HBY8 UniRef50: UniRef50_Q9HBY8 UniGene: Hs.300863, Hs.740147 CCDS: CCDS13321.1, CCDS13320.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32848212	Serum- and glucocorticoid- inducible kinase 2, SGK2, is a novel autophagy regulator and modulates platinum drugs response in cancer cells. Oncogene Valentina Ranzuglia , Ilaria Lorenzon , Ilenia Pellarin , Maura Sonego , Alessandra Dall'Acqua , Sara D'Andrea , Sara Lovisa , Ilenia Segatto , Michela Coan , Jerry Polesel , Diego Serraino , Patrizia Sabatelli , Paola Spessotto , Barbara Belletti , Gustavo Baldassarre , Monica Schiappacassi	2020-10-01	-
32565024	SGK2 is overexpressed in colon cancer and promotes epithelial-mesenchymal transition in colon cancer cells. Eur J Surg Oncol Yang Liu , Junying Liu , Xin Kong , Han Li , Jianying Shao , Ziting Jiang	2020-10-01	-
32296183	A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G CotÃ© , Meaghan Daley , Steven Deimling , Alice Desbuleux , AmÃ©lie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , IstvÃ¡n A KovÃ¡cs , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood	2020-04-01	-
31002126	SGK2 promotes renal cancer progression via enhancing ERK 1/2 and AKT phosphorylation. Eur Rev Med Pharmacol Sci Y Liu , J-B Chen , M Zhang , X-L Zhang , J-L Meng , J Zhou , Z-Y Hao , L Zhang , X-B Zu , C-Z Liang	2019-04-01	-
29513927	Comparative Protein Interaction Network Analysis Identifies Shared and Distinct Functions for the Human ROCO Proteins. Proteomics James E Tomkins , Sybille Dihanich , Alexandra Beilina , Raffaele Ferrari , NicolÃ² Ilacqua , Mark R Cookson , Patrick A Lewis , Claudia Manzoni	2018-05-01	-
28846114	Identification of translationally controlled tumor protein in promotion of DNA homologous recombination repair in cancer cells by affinity proteomics. Oncogene Y Li , H Sun , C Zhang , J Liu , H Zhang , F Fan , R A Everley , X Ning , Y Sun , J Hu , J Liu , J Zhang , W Ye , X Qiu , S Dai , B Liu , H Xu , S Fu , S P Gygi , C Zhou	2017-12-14	-
28611215	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc. Natl. Acad. Sci. U.S.A. Teng Fei , Yiwen Chen , Tengfei Xiao , Wei Li , Laura Cato , Peng Zhang , Maura B Cotter , Michaela Bowden , Rosina T Lis , Shuang G Zhao , Qiu Wu , Felix Y Feng , Massimo Loda , Housheng Hansen He , X Shirley Liu , Myles Brown	2017-06-27	-
28639896	SGK2 promotes hepatocellular carcinoma progression and mediates GSK-3Î²/Î²-catenin signaling in HCC cells. Tumour Biol Junying Liu , Guangdong Zhang , Yanping Lv , Xiaoyang Zhang , Cui Ying , Suocheng Yang , Xin Kong , Yanzhang Yu	2017-06-01	-
27553422	Parental origin of the deletion del(20q) in Shwachman-Diamond patients and loss of the paternally derived allele of the imprinted L3MBTL1 gene. Genes Chromosomes Cancer Lucia Nacci , Roberto Valli , Rita Maria Pinto , Marco Zecca , Marco Cipolli , Jacopo Morini , Simone Cesaro , Emanuela Boveri , Vittorio Rosti , Paola Corti , Maura Ambroni , Francesco Pasquali , Cesare Danesino , Emanuela Maserati , Antonella Minelli	2017-01-01	-
26740304	Serum- and glucocorticoid-inducible kinase SGK2 regulates human organic anion transporters 4 via ubiquitin ligase Nedd4-2. Biochem. Pharmacol. Haoxun Wang , Da Xu , May Fern Toh , Alan C Pao , Guofeng You	2016-02-15	SGK2, NEDD4L, SLC22A11

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