| Type | Description |
|---|---|
| Definition | elastin microfibril interfacer 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 10:30:00 | Study demonstrated that EMILIN-1, by virtue of its interaction with beta1 integrins, is centrally located in the contest of colitis-associated cancer (CAC) by controlling the process of proliferation, tumor development and counteracting lymphatic dysfunction associated with chronic colonic inflammation. | 31479698 |
| 2019-08-10 10:53:00 | Increased blood pressure in mice with selective smooth muscle cell ablation of EMILIN-1 depends on transactivation of EGFR and enhanced myogenic tone. | 30354220 |
| 2019-01-26 12:40:00 | EMILIN-1 plays a role in the formation and maintenance of the elastic fiber system in the aorta but is not absolutely mandatory for the overall function of fibulin-4 or fibulin-5 in this microenvironment. | 28717224 |
| 2015-10-10 11:25:00 | Data suggested mechanisms for homo- and hetero-typic EMILINs multimers formation: EMILIN1 or EMILIN2 alone can form trimers and multimers in the absence of each other or they can co-polymerize in a head-to-tail fashion to form hetero-typic multimers. | 25445627 |
| 2015-04-04 10:59:00 | Emilin1 deficiency results in aortic valve disease, mediated by non-canonical (MAPK/phosphorylated Erk1 and Erk2) TGF-beta dysregulation. | 25056700 |
| Type | IDs |
|---|---|
| Synonymous | 5830419M17Rik, AW229038, BB105748, EMILIN-1, gp115 |
| Gene |
UniProtKB-ID:
EMIL1_MOUSE
UniprotKB:
Q99K41
UniParc:
UPI0000023100
EMBL:
BC005481,
AK029337
Ensembl:
ENSMUSG00000029163
KO:
mmu:100952
|
| Nucleutide sequences |
EMBL-CDS:
AAH05481.1,
BAC26403.1
Ensembl_TRS:
ENSMUST00000031055
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000031055
RefSeq:
NP_598679.1,
XP_006503712.1
|
| Others |
UniRef100:
UniRef100_Q99K41
UniRef90:
UniRef90_Q99K41
UniRef50:
UniRef50_Q9Y6C2
UniGene:
Mm.286375
CCDS:
CCDS19167.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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