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1009 CDH11

1009

CDH11

cadherin 11

protein-coding

Homo sapiens

基因描述

Type Description
Definition cadherin 11

研究结论

Date Results Publications
2021-02-06 13:52:00 CpG Islands Methylation Analysis of CDH11, EphA5, and HS3ST2 Genes in Gastric Adenocarcinoma Patients. 31407253
2020-06-27 11:40:00 CDH11 was a reliable therapeutic target in bladder cancer. 31894237
2020-06-27 11:33:00 This study demonstrated that EPHB6-mutated cells acquire cell adhesion-mediated drug resistance (CAM-DR) in association with CDH11 expression and RhoA/focal adhesion kinase (FAK) activation. Targeted inhibition of EPHA2 or CDH11 reversed the acquired paclitaxel resistance, suggesting its potential clinical utility. 31160603
2020-02-08 11:35:00 Interactions between cadherin-11 and PDGFRalpha signaling link cell adhesion and cell proliferation. 30876808
2019-11-30 11:59:00 CDH11 is an inductor of metastatic signaling, and biomarker of poor prognosis in metastatic breast cells (MBCs). Exposure to anti-CDH11 antibody suppresses metastasis, reduces CDH11, fibronectin and beta-catenin expression, and abrogate the cancer stem cell-like traits of MBC cells. Ectopic expression of miR-335 suppresses CDH11, beta-catenin and vimentin expression, in concert with attenuated metastatic potentials. 31248373

名称对应

Type IDs
Synonymous CAD11, CDHOB, ESWS, OB, OSF-4
Gene
UniProtKB-ID: CAD11_HUMAN, H3BUU9_HUMAN
UniprotKB: P55287, H3BUU9
UniParc: UPI000013D7C5, UPI0002466E93, UPI000016039D
EMBL: AF060370, L34056, D21254, AC010533, AF060369, D21255, AC137643, AK291251
Ensembl: ENSG00000140937
KO: hsa:1009
Nucleutide sequences
EMBL-CDS: AAD27755.1, AAA35622.1, BAA04799.1, AAD27756.1, BAF83940.1, BAA04798.1
Ensembl_TRS: ENST00000394156, ENST00000268603, ENST00000566827
Protein sequencees
Ensembl_PRO: ENSP00000268603, ENSP00000377711, ENSP00000457812
RefSeq: XP_011521105.1, NP_001295321.1, NP_001317505.1, XP_005255820.1, NP_001788.2, XP_005255819.1, XP_024305902.1
Others
UniRef100: UniRef100_P55287
UniRef90: UniRef90_P55287
UniRef50: UniRef50_P55287
UniGene: Hs.116471
CCDS: CCDS10803.1, CCDS81993.1

全选

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