| Type | Description |
|---|---|
| Definition | acetyl-Coenzyme A carboxylase beta |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 13:07:00 | Using mice with Ser(79)Ala/Ser(212)Ala knock-in mutations (ACC DKI) the authors find that inhibition of ACC phosphorylation leads to reduced appetite in response to fasting or cold exposure. | 29433631 |
| 2019-07-20 11:00:00 | AMPK-ACC signaling is coupled to the control of thrombosis by specifically modulating thromboxane and granule release in response to collagen. | 30018077 |
| 2019-03-02 11:41:00 | Findings suggest that ACC2 deletion leads to intramyocellular lipid reduction without suppressing glucose use via an elevation in acetyl-CoA metabolism even under high-fat diet conditions and offer new mechanistic insight into the therapeutic potential of ACC2 inhibition on insulin resistance. | 29931154 |
| 2018-11-17 10:55:00 | Lipogenesis is dispensable for liver tumorigenesis in mice treated with diethylnitrosamine, and ACC enzymes have an important role in redox regulation and cell survival. | 28290443 |
| 2018-04-21 10:40:00 | of ACCs decreased polyunsaturated fatty acid (PUFA) concentrations in liver due to reduced malonyl-CoA, which is required for elongation of essential fatty acids. | 28768177 |
| Type | IDs |
|---|---|
| Synonymous | AI597064, AW743042, Acc2, Accb |
| Gene |
UniProtKB-ID:
ACACB_MOUSE,
Q3UHC8_MOUSE,
Q9ESZ3_MOUSE
UniprotKB:
E9Q4Z2,
Q3UHC8,
Q9ESZ3
UniParc:
UPI00005AC664,
UPI0000021616,
UPI0000D77AB2
EMBL:
AY451394,
AC122282,
AK147463,
AF290178
Ensembl:
ENSMUSG00000042010
KO:
mmu:100705
|
| Nucleutide sequences |
EMBL-CDS:
AAS13686.1,
BAE27929.1,
AAG01860.2
Ensembl_TRS:
ENSMUST00000031583,
ENSMUST00000102582
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099642,
ENSMUSP00000031583
RefSeq:
XP_006530177.1,
XP_006530174.1,
XP_006530176.1,
XP_006530175.1,
NP_598665.2
|
| Others |
UniRef100:
UniRef100_Q8C697,
UniRef100_E9Q4Z2,
UniRef100_Q3UHC8
UniRef90:
UniRef90_E9Q4Z2,
UniRef90_Q3UHC8
UniRef50:
UniRef50_E9Q4Z2,
UniRef50_A0A672PKD8
UniGene:
Mm.81793
CCDS:
CCDS19561.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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