| Type | Description |
|---|---|
| Definition | scribble planar cell polarity protein |
| Date | Results | Publications |
|---|---|---|
| 2020-05-23 10:05:00 | SGEF plays a key role in coordinating junctional assembly and actomyosin contractility by bringing together Scribble and Dlg1 and targeting RhoG activation to cell-cell junctions. | 31248911 |
| 2018-07-07 10:59:00 | MDCK cells silenced for the polarity gene scribble (scrib(KD)) are hypersensitive to compaction. | 27109213 |
| 2013-06-08 12:50:00 | Scribble-knockdown cells undergo apoptosis and are apically extruded from the epithelium when surrounded by normal cells | 22250205 |
| 2013-06-01 10:02:00 | Depletion of Scrb enhances endocytosis of E-cadherin by weakening the E-cadherin-p120catenin interaction. | 23226478 |
| 2013-05-11 12:17:00 | The molecular chaperone HSP90 is also required for Sgt1 association with Scrib, and both Sgt1 and HSP90 are needed to ensure proper Scrib protein levels. | 22623728 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
F1PKY2_CANLF
UniprotKB:
F1PKY2
UniParc:
UPI0006B3CAA9
EMBL:
AAEX03008939,
AAEX03008940
Ensembl:
ENSCAFG00000001372
KO:
cfa:100685037
|
| Nucleutide sequences |
Ensembl_TRS:
ENSCAFT00000002152
|
| Protein sequencees |
Ensembl_PRO:
ENSCAFP00000001992
RefSeq:
XP_013974216.2
|
| Others |
UniRef100:
UniRef100_F1PKY2
UniRef90:
UniRef90_A0A5F4CAL4
UniRef50:
UniRef50_Q80U72
UniGene:
Cfa.31836
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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