| Type | Description |
|---|---|
| Definition | Rac family small GTPase 1 |
| Date | Results | Publications |
|---|---|---|
| 2015-05-02 12:14:00 | In conclusion, our observations reveal that PRRSV triggers the activation of FAK-PI3K-AKT-Rac1 signaling pathway to facilitate its entry into cells. | 25660453 |
| 2013-09-21 12:39:00 | Data indicate that TNF-alpha stimulates Rac, ADAM17/TACE, and RhoA through the guanine nucleotide exchange factor (GEF)-H1. | 23389627 |
| 2011-08-23 05:35:00 | Using the model of porcine aortic endothelial cells, we demonstrated that TGFbeta stimulates cellular spreading when cells are on collagen I; TGFbeta-stimulated Rac1-GTP accumulation, which was associated with increased MAPK p38 phosphorylation. | 18387002 |
| 2011-08-23 05:35:00 | Results suggest that Rac1 and RhoA are regulated by TGFbeta1 in the process of endothelial tube formation in collagen I gels. | 16978608 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
A0A4X1TUU9_PIG
UniprotKB:
A0A4X1TUU9
UniParc:
UPI000000060F
Ensembl:
ENSSSCG00070011854
KO:
ssc:100627149
|
| Nucleutide sequences |
Ensembl_TRS:
ENSSSCT00070023126
|
| Protein sequencees |
Ensembl_PRO:
ENSSSCP00070019123
RefSeq:
NP_001230514.1,
XP_020941412.1
|
| Others |
UniRef100:
UniRef100_P63000
UniRef90:
UniRef90_P63000
UniRef50:
UniRef50_P63000
UniGene:
Ssc.7247
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 25660453 |
Biochem. Biophys. Res. Commun. Bo Ni , Li-Bin Wen , Rui Wang , Hong-Ping Hao , Chang-Chao Huan , Xin Wang , Li Huang , Jin-Feng Miao , Hong-Jie Fan , Xiang Mao |
2015-03-06 |
AKT1,
PTK2,
RAC3,
PIK3CG
|
| 23389627 |
Mol. Biol. Cell Faiza Waheed , Qinghong Dan , Yasaman Amoozadeh , Yuqian Zhang , Susumu Tanimura , Pam Speight , András Kapus , Katalin Szászi |
2013-04-01 |
ARHGEF2,
RAC3,
RHOA,
ADAM17
|
| 18387002 |
TGFbeta1 regulates endothelial cell spreading and hypertrophy through a Rac-p38-mediated pathway. Biol. Cell Christine Varon , Patricia Rottiers , Jerome Ezan , Edith Reuzeau , Caroline Basoni , Ijsbrand Kramer , Elisabeth Génot |
2008-09-01 |
RAC3,
TGFB1
|
| 16978608 |
TGFbeta1-induced aortic endothelial morphogenesis requires signaling by small GTPases Rac1 and RhoA. Exp. Cell Res. Christine Varon , Caroline Basoni , Edith Reuzeau , Violaine Moreau , I Jsbrand Kramer , Elisabeth Génot |
2006-11-01 |
RAC3,
RHOA,
TGFB1
|
| 16428270 |
Am J Physiol Lung Cell Mol Physiol Beata Wojciak-Stothard , Lillian Yen Fen Tsang , Ewa Paleolog , Susan M Hall , Sheila G Haworth |
2006-06-01 | - |
| 16129884 |
Polarized downregulation of the paxillin-p130CAS-Rac1 pathway induced by shear flow. J. Cell. Sci. Ronen Zaidel-Bar , Zvi Kam , Benjamin Geiger |
2005-09-01 |
PXN,
BCAR1,
RAC3
|
| 15679890 |
Comparative analysis of protein coding sequences from human, mouse and the domesticated pig. BMC Biol. Frank Grønlund Jørgensen , Asger Hobolth , Henrik Hornshøj , Christian Bendixen , Merete Fredholm , Mikkel Heide Schierup |
2005-01-01 |
NREP,
P4HA1,
LOC100037988,
RPL14,
RPL27,
RPS26,
SNRPE,
EIF4E2,
ACOX1,
COPS5,
COPS2,
COPS4,
CD302,
CNPY3,
GATM,
SUMO1,
LMO4,
HNRNPAB,
SMNDC1,
CAPZB,
PRELID3B,
AIMP1,
SPCS1,
DEGS1,
H2AFZ,
RPL7L1,
PON2,
HEXA,
UCHL5,
RAB34,
RAB5A,
RNF5,
PHGDH,
ITLN2,
TMCO1,
TAF11,
RAB2A,
VIMP,
SDCBP,
ARV1,
PMP2,
MRPL2,
TPD52,
AIG1,
C1H15orf61,
LOC100152047,
ENPP6,
COMMD4,
POLR3GL,
PLEKHO1,
SSB,
CMSS1,
AGA,
CUTA,
PEX7,
COX6A1,
PMVK,
MTERF3,
CD53,
FRZB,
PEA15,
ERH,
TMEM242,
CTHRC1,
MED6,
FAM162B,
FAM204A,
PDZK1,
DPCD,
HAUS1,
COQ10B,
BNIP3L,
SSR1,
MRPS28,
SDC2,
DHRS7,
TOMM20,
DNAJB11,
BZW1,
CXHXorf56,
GNPNAT1,
BOLA1,
PDCD7,
PFDN6,
LOC100153062,
DTWD1,
UBE2C,
STK16,
DNPEP,
ARPC2,
SIT1,
STX7,
WDR61,
PPP6C,
TIPIN,
MYF5,
MRPL13,
CHCHD1,
EAPP
|
| 14681463 |
Nucleic Acids Res. Hirohide Uenishi , Tomoko Eguchi , Kohei Suzuki , Tetsuya Sawazaki , Daisuke Toki , Hiroki Shinkai , Naohiko Okumura , Noriyuki Hamasima , Takashi Awata |
2004-01-01 |
PIK3R6,
DESI2,
ENPP1,
SPARCL1,
NREP,
SLA-3,
IRF7,
DYNC1H1,
SLA-1,
P4HA1,
DNMT3A,
SEPHS2,
SGMS1,
CPE,
BIN1,
TNFRSF1B,
SLA-DQB1,
CD14,
APOBEC3F,
PDE4B,
KCND3,
KCNIP2,
UIMC1,
LOC100037950,
C9,
C6,
C8A,
C8B,
C8G,
LOC100037957,
CAPZA2,
CTSB,
SEPP1,
LOC100037968,
SLC7A7,
C2H19orf70,
ATP5J2,
PET100,
TOMM7,
NDUFC1,
SLIRP,
LOC100037988,
COX6C,
COX7C,
NDUFV2,
PSMB7,
RPL10A,
RPL14,
RPL27,
RPS21,
RPS26,
TMSB10,
TPM1,
ATPIF1,
KLF7,
RCHY1,
PCD1B,
CD1E,
SEP15,
CCL11,
CD72,
PVRL2,
COX6B,
RPS6,
CLEC7A,
RPL4,
EIF4E,
LGALS3,
SNRPE,
ZFAND5,
ADSS,
SDHD,
C5AR1,
BTG3,
GNA14,
NAGS,
TNMD,
ABCG8,
YWHAQ,
PGRMC2,
CYB561,
CNN3,
GNAS,
RBM39,
BRCA1,
EDN3,
KRT2,
HPS4,
BLOC1S5,
BLOC1S6,
RABGGTA,
MLPH,
ATP7B,
CRYZL1,
PNPLA3,
SRGN,
SPTAN1,
BIRC6,
HPS5
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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