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100616072 Snord116

100616072

Snord116

small nucleolar RNA, C/D box 116 cluster

other

Mus musculus

基因描述

Type Description
Definition small nucleolar RNA, C/D box 116 cluster

研究结论

Date Results Publications
2019-05-18 10:50:00 Knockdown of Rbfox3, encoding neuron-specific splicing factor neuronal nuclei (NeuN) in Snord116+/--derived neurons, reduced splicing of the transgene in neurons... these results demonstrate that exogenous expression and neuron-specific splicing of the Snord116 locus are insufficient to rescue the genetic deficiency of Snord116 paternal deletion 30124848
2019-02-09 10:30:00 A major genetic effect on rhythmic methylation in a mouse Snord116 deletion model of the imprinted disorder Prader-Willi syndrome. 29691382
2018-06-09 10:30:00 Data indicate that the metabolic symptoms of Prader-Willi syndrome develop gradually and the Snord116 gene plays a critical role during this process. 28094877
2017-03-11 11:08:00 Our study highlights that the function of Snord116 in the hypothalamus may be to enhance energy expenditure, likely via the NPY system, and also indicates that Snord116 function in mice is strongly dependent on environmental conditions such as cold exposure. 27823858
2016-12-24 10:11:00 snord116 RNA mutants have a bilateral reduction of the gray matter volume in the ventral hippocampus and in the septum areas, which are pivotal structures for maintaining theta rhythms throughout the brain 26446116

名称对应

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Type IDs
Synonymous MBII-85, Pwcr1