| Type | Description |
|---|---|
| Definition | ATP binding cassette subfamily C member 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:32:00 | MRP5 nitration by NO-releasing gemcitabine encapsulated in liposomes confers sensitivity in chemoresistant pancreatic adenocarcinoma cells. | 32828758 |
| 2018-04-21 12:07:00 | ABCC5 polymorphisms may explain partially the interpatient variability in doxorubicin disposition. | 26975227 |
| 2017-11-04 11:55:00 | This study is the first to identify the roles of FOXM1 in drug efflux and paclitaxel resistance by regulating the gene transcription of abcc5, one of the ABC transporters. Small molecular inhibitors of FOXM1 or ABCC5 have the potential to overcome paclitaxel chemoresistance in nasopharyngeal carcinoma (NPC)patients. | 28277541 |
| 2017-08-26 11:56:00 | These findings enrich the allelic spectrum of ABCC5 in PACG. We identified no tagging SNP responsible for the association of the whole region. | 28813580 |
| 2017-08-12 10:43:00 | Survivors of childhood acute lymphoblastic leukemia treated with doxorubicin with the ABCC5 TT-1629 genotype had an average of 8-12% reduction of ventricular ejection and shortening fractions. | 26345518 |
| Type | IDs |
|---|---|
| Synonymous | ABC33, EST277145, MOAT-C, MOATC, MRP5, SMRP, pABC11 |
| Gene |
UniProtKB-ID:
MRP5_HUMAN
UniprotKB:
O15440
UniParc:
UPI000018CED4,
UPI000004A33C,
UPI000020A885,
UPI00006C6535,
UPI0000192115
EMBL:
AB019002,
CH471052,
AC068644,
AY196484,
U83661,
AB005659,
BC140771,
BC050744,
AY754876,
AY754875,
BC142719,
AF104942,
AF146074,
AY754874
Ensembl:
ENSG00000114770
KO:
hsa:10057
|
| Nucleutide sequences |
EMBL-CDS:
AAD37716.1,
BAA76608.1,
AAI40772.1,
EAW78308.1,
AAH50744.1,
AAD04169.1,
AAW82948.1,
EAW78307.1,
BAA22887.1,
AAW82950.1,
AAI42720.1,
AAO49801.1,
AAW82949.1,
AAB71758.2
Ensembl_TRS:
ENST00000265586,
ENST00000392579,
ENST00000382494,
ENST00000334444,
ENST00000443376
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000333926,
ENSP00000416840,
ENSP00000371934,
ENSP00000265586,
ENSP00000376358
RefSeq:
XP_011510617.1,
XP_005247115.1,
XP_024309054.1,
XP_016860982.1,
NP_001018881.1,
XP_016860981.1,
NP_005679.2,
XP_016860983.1,
XP_005247116.1,
XP_011510616.1,
NP_001306961.1
|
| Others |
UniRef100:
UniRef100_O15440
UniRef90:
UniRef90_O15440
UniRef50:
UniRef50_O15440
UniGene:
Hs.368563,
Hs.743953
CCDS:
CCDS43176.1,
CCDS33898.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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