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10055 SAE1

10055

SAE1

SUMO1 activating enzyme subunit 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition SUMO1 activating enzyme subunit 1

研究结论

Date Results Publications
2020-12-26 13:11:00 SUMOylation of the transcription factor ZFHX3 at Lys-2806 requires SAE1, UBC9, and PIAS2 and enhances its stability and function in cell proliferation. 32249212
2020-06-20 10:22:00 SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling 31345225
2015-11-21 10:54:00 the expression of SENP8, SAE1, PIAS1, PIAS2 and ZMIZ1 is deregulated in the majority of PTC tissues, likely contributing to the PTC phenotype. 26403403
2015-04-18 11:48:00 as it has been shown by flow cytometry analysis, specific knockdown of SAE1 slowed down the cell population at G0/G1 phase and induced apoptosis of RKO cells. 25842831
2012-12-08 11:28:00 Data indicate the role of anti-SUMO activating enzyme SAE1 and SAE2 antibody as marker of dermatomyositis. 22884621

名称对应

Type IDs
Synonymous AOS1, HSPC140, SUA1, UBLE1A
Gene
UniProtKB-ID: SAE1_HUMAN, A0A024R0R4_HUMAN
UniprotKB: Q9UBE0, A0A024R0R4
UniParc: UPI000059D753, UPI0000D4CF03, UPI0000037725
EMBL: AL560234, CH471126, BC018271, AC008755, AF090385, AK315624, BC000344, AF110956, BT007290, AK021978, BC003611, AF046025, AF161489, AC008532
Ensembl: ENSG00000142230
KO: hsa:10055
Nucleutide sequences
EMBL-CDS: EAW57463.1, AAD23902.2, BAG51064.1, EAW57461.1, AAH18271.1, AAH03611.1, AAD12785.2, AAP35954.1, AAH00344.1, AAF29104.1, AAD24433.1, BAG37992.1, EAW57462.1
Gene_ORFName: hCG_20373
Ensembl_TRS: ENST00000270225, ENST00000413379, ENST00000392776
Protein sequencees
Ensembl_PRO: ENSP00000416557, ENSP00000440818, ENSP00000270225
RefSeq: NP_001139185.1, NP_001139186.1, NP_005491.1
Others
UniRef100: UniRef100_Q9UBE0
UniRef90: UniRef90_Q9UBE0
UniRef50: UniRef50_Q9UBE0
UniGene: Hs.515500
CCDS: CCDS54284.1, CCDS54285.1, CCDS12696.1

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