| Type | Description |
|---|---|
| Definition | ubiquitin like modifier activating enzyme 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:04:00 | Identifying UBA2 as a proliferation and cell cycle regulator in lung cancer A549 cells. | 30848500 |
| 2020-07-18 10:26:00 | the results together with previous data such as the development of Split-hand/foot malformation (SHFM) in Lrp6 knockout mice, the presence of SHFM in two subjects with 19q13 deletions involving UBA2, and strong mouse Uba2 expression in the developing limb buds, imply that LRP6 and UBA2 represent plausible candidate genes for SHFM. | 31332306 |
| 2019-09-21 12:19:00 | The findings suggest that the UBA2-WTIP fusion is an oncogenic fusion gene, as well as a promising therapeutic target for the treatment of acute myeloid leukemia. | 30179602 |
| 2019-05-18 12:09:00 | the results suggest that Uba2 participates in the progression, invasion, and metastasis of colorectal cancer, and the possible mechanism is via regulating the Wnt signaling pathway and enhancing epithelial-mesenchymal transition behaviors of colorectal cancer cells. | 29744931 |
| 2019-02-02 11:22:00 | results from the present study indicated that UBA2 expression may enhance colorectal cancer cell proliferation and inhibit apoptosis. | 30387828 |
| Type | IDs |
|---|---|
| Synonymous | ARX, HRIHFB2115, SAE2 |
| Gene |
UniProtKB-ID:
SAE2_HUMAN
UniprotKB:
Q9UBT2
UniParc:
UPI0000E25113,
UPI000004F09F
EMBL:
AF079566,
BC003153,
AB015337,
CR456756,
AF090384,
BT009781,
U35832,
AC008747,
AF110957,
AK124730,
AL136905,
AB208872
Ensembl:
ENSG00000126261
KO:
hsa:10054
|
| Nucleutide sequences |
EMBL-CDS:
BAA34795.1,
BAD92109.1,
AAC99992.1,
AAD24434.1,
BAG54081.1,
AAH03153.1,
CAG33037.1,
AAD12784.1,
AAD23914.1,
AAP88783.1,
CAB66839.1
Gene_ORFName:
HRIHFB2115
Ensembl_TRS:
ENST00000439527,
ENST00000246548
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000246548,
ENSP00000437484
RefSeq:
XP_016881623.1,
XP_024307073.1,
XP_006723025.1,
XP_011524606.1,
XP_005258461.2,
NP_005490.1
|
| Others |
UniRef100:
UniRef100_Q9UBT2
UniRef90:
UniRef90_Q9UBT2
UniRef50:
UniRef50_Q9UBT2
UniGene:
Hs.631580
CCDS:
CCDS12439.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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