RNA-binding activity of TRIM25 is mediated by its PRY/SPRY domain and is required for ubiquitination.

BMC Biol     Nila Roy Choudhury , Gregory Heikel , Maryia Trubitsyna , Peter Kubik , Jakub Stanislaw Nowak , Shaun Webb , Sander Granneman , Christos Spanos , Juri Rappsilber , Alfredo Castello , Gracjan Michlewski

Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.

Nat. Genet.     DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium , Asian Genetic Epidemiology Network Type 2 Diabetes (AGEN-T2D) Consortium , South Asian Type 2 Diabetes (SAT2D) Consortium , Mexican American Type 2 Diabetes (MAT2D) Consortium , Type 2 Diabetes Genetic Exploration by Nex-generation sequencing in muylti-Ethnic Samples (T2D-GENES) Consortium , Anubha Mahajan , Min Jin Go , Weihua Zhang , Jennifer E Below , Kyle J Gaulton , Teresa Ferreira , Momoko Horikoshi , Andrew D Johnson , Maggie C Y Ng , Inga Prokopenko , Danish Saleheen , Xu Wang , Eleftheria Zeggini , Goncalo R Abecasis , Linda S Adair , Peter Almgren , Mustafa Atalay , Tin Aung , Damiano Baldassarre , Beverley Balkau , Yuqian Bao , Anthony H Barnett , Ines Barroso , Abdul Basit , Latonya F Been , John Beilby , Graeme I Bell , Rafn Benediktsson , Richard N Bergman , Bernhard O Boehm , Eric Boerwinkle , Lori L Bonnycastle , Noël Burtt , Qiuyin Cai , Harry Campbell , Jason Carey , Stephane Cauchi , Mark Caulfield , Juliana C N Chan , Li-Ching Chang , Tien-Jyun Chang , Yi-Cheng Chang , Guillaume Charpentier , Chien-Hsiun Chen , Han Chen , Yuan-Tsong Chen , Kee-Seng Chia , Manickam Chidambaram , Peter S Chines , Nam H Cho , Young Min Cho , Lee-Ming Chuang , Francis S Collins , Marylin C Cornelis , David J Couper , Andrew T Crenshaw , Rob M van Dam , John Danesh , Debashish Das , Ulf de Faire , George Dedoussis , Panos Deloukas , Antigone S Dimas , Christian Dina , Alex S Doney , Peter J Donnelly , Mozhgan Dorkhan , Cornelia van Duijn , Josée Dupuis , Sarah Edkins , Paul Elliott , Valur Emilsson , Raimund Erbel , Johan G Eriksson , Jorge Escobedo , Tonu Esko , Elodie Eury , Jose C Florez , Pierre Fontanillas , Nita G Forouhi , Tom Forsen , Caroline Fox , Ross M Fraser , Timothy M Frayling , Philippe Froguel , Philippe Frossard , Yutang Gao , Karl Gertow , Christian Gieger , Bruna Gigante , Harald Grallert , George B Grant , Leif C Grrop , Chrisropher J Groves , Elin Grundberg , Candace Guiducci , Anders Hamsten , Bok-Ghee Han , Kazuo Hara , Neelam Hassanali , Andrew T Hattersley , Caroline Hayward , Asa K Hedman , Christian Herder , Albert Hofman , Oddgeir L Holmen , Kees Hovingh , Astradur B Hreidarsson , Cheng Hu , Frank B Hu , Jennie Hui , Steve E Humphries , Sarah E Hunt , David J Hunter , Kristian Hveem , Zafar I Hydrie , Hiroshi Ikegami , Thomas Illig , Erik Ingelsson , Muhammed Islam , Bo Isomaa , Anne U Jackson , Tazeen Jafar , Alan James , Weiping Jia , Karl-Heinz Jöckel , Anna Jonsson , Jeremy B M Jowett , Takashi Kadowaki , Hyun Min Kang , Stavroula Kanoni , Wen Hong L Kao , Sekar Kathiresan , Norihiro Kato , Prasad Katulanda , Kirkka M Keinanen-Kiukaanniemi , Ann M Kelly , Hassan Khan , Kay-Tee Khaw , Chiea-Chuen Khor , Hyung-Lae Kim , Sangsoo Kim , Young Jin Kim , Leena Kinnunen , Norman Klopp , Augustine Kong , Eeva Korpi-Hyövälti , Sudhir Kowlessur , Peter Kraft , Jasmina Kravic , Malene M Kristensen , S Krithika , Ashish Kumar , Jesus Kumate , Johanna Kuusisto , Soo Heon Kwak , Markku Laakso , Vasiliki Lagou , Timo A Lakka , Claudia Langenberg , Cordelia Langford , Robert Lawrence , Karin Leander , Jen-Mai Lee , Nanette R Lee , Man Li , Xinzhong Li , Yun Li , Junbin Liang , Samuel Liju , Wei-Yen Lim , Lars Lind , Cecilia M Lindgren , Eero Lindholm , Ching-Ti Liu , Jian Jun Liu , Stéphane Lobbens , Jirong Long , Ruth J F Loos , Wei Lu , Jian'an Luan , Valeriya Lyssenko , Ronald C W Ma , Shiro Maeda , Reedik Mägi , Satu Männisto , David R Matthews , James B Meigs , Olle Melander , Andres Metspalu , Julia Meyer , Ghazala Mirza , Evelin Mihailov , Susanne Moebus , Viswanathan Mohan , Karen L Mohlke , Andrew D Morris , Thomas W Mühleisen , Martina Müller-Nurasyid , Bill Musk , Jiro Nakamura , Eitaro Nakashima , Pau Navarro , Peng-Keat Ng , Alexandra C Nica , Peter M Nilsson , Inger Njølstad , Markus M Nöthen , Keizo Ohnaka , Twee Hee Ong , Katharine R Owen , Colin N A Palmer , James S Pankow , Kyong Soo Park , Melissa Parkin , Sonali Pechlivanis , Nancy L Pedersen , Leena Peltonen , John R B Perry , Annette Peters , Janini M Pinidiyapathirage , Carl G Platou , Simon Potter , Jackie F Price , Lu Qi , Venkatesan Radha , Loukianos Rallidis , Asif Rasheed , Wolfgang Rathman , Rainer Rauramaa , Soumya Raychaudhuri , N William Rayner , Simon D Rees , Emil Rehnberg , Samuli Ripatti , Neil Robertson , Michael Roden , Elizabeth J Rossin , Igor Rudan , Denis Rybin , Timo E Saaristo , Veikko Salomaa , Juha Saltevo , Maria Samuel , Dharambir K Sanghera , Jouko Saramies , James Scott , Laura J Scott , Robert A Scott , Ayellet V Segrè , Joban Sehmi , Bengt Sennblad , Nabi Shah , Sonia Shah , A Samad Shera , Xiao Ou Shu , Alan R Shuldiner , Gunnar Sigurđsson , Eric Sijbrands , Angela Silveira , Xueling Sim , Suthesh Sivapalaratnam , Kerrin S Small , Wing Yee So , Alena Stančáková , Kari Stefansson , Gerald Steinbach , Valgerdur Steinthorsdottir , Kathleen Stirrups , Rona J Strawbridge , Heather M Stringham , Qi Sun , Chen Suo , Ann-Christine Syvänen , Ryoichi Takayanagi , Fumihiko Takeuchi , Wan Ting Tay , Tanya M Teslovich , Barbara Thorand , Gudmar Thorleifsson , Unnur Thorsteinsdottir , Emmi Tikkanen , Joseph Trakalo , Elena Tremoli , Mieke D Trip , Fuu Jen Tsai , Tiinamaija Tuomi , Jaakko Tuomilehto , Andre G Uitterlinden , Adan Valladares-Salgado , Sailaja Vedantam , Fabrizio Veglia , Benjamin F Voight , Congrong Wang , Nicholas J Wareham , Roman Wennauer , Ananda R Wickremasinghe , Tom Wilsgaard , James F Wilson , Steven Wiltshire , Wendy Winckler , Tien Yin Wong , Andrew R Wood , Jer-Yuarn Wu , Ying Wu , Ken Yamamoto , Toshimasa Yamauchi , Mingyu Yang , Loic Yengo , Mitsuhiro Yokota , Robin Young , Delilah Zabaneh , Fan Zhang , Rong Zhang , Wei Zheng , Paul Z Zimmet , David Altshuler , Donald W Bowden , Yoon Shin Cho , Nancy J Cox , Miguel Cruz , Craig L Hanis , Jaspal Kooner , Jong-Young Lee , Mark Seielstad , Yik Ying Teo , Michael Boehnke , Esteban J Parra , Jonh C Chambers , E Shyong Tai , Mark I McCarthy , Andrew P Morris

Genome-wide association study identifies three novel loci for type 2 diabetes.

Hum. Mol. Genet.     Kazuo Hara , Hayato Fujita , Todd A Johnson , Toshimasa Yamauchi , Kazuki Yasuda , Momoko Horikoshi , Chen Peng , Cheng Hu , Ronald C W Ma , Minako Imamura , Minoru Iwata , Tatsuhiko Tsunoda , Takashi Morizono , Nobuhiro Shojima , Wing Yee So , Ting Fan Leung , Patrick Kwan , Rong Zhang , Jie Wang , Weihui Yu , Hiroshi Maegawa , Hiroshi Hirose , DIAGRAM consortium , Kohei Kaku , Chikako Ito , Hirotaka Watada , Yasushi Tanaka , Kazuyuki Tobe , Atsunori Kashiwagi , Ryuzo Kawamori , Weiping Jia , Juliana C N Chan , Yik Ying Teo , Tai E Shyong , Naoyuki Kamatani , Michiaki Kubo , Shiro Maeda , Takashi Kadowaki

Genome-wide association study in individuals of South Asian ancestry identifies six new type 2 diabetes susceptibility loci.

Nat. Genet.     Jaspal S Kooner , Danish Saleheen , Xueling Sim , Joban Sehmi , Weihua Zhang , Philippe Frossard , Latonya F Been , Kee-Seng Chia , Antigone S Dimas , Neelam Hassanali , Tazeen Jafar , Jeremy B M Jowett , Xinzhong Li , Venkatesan Radha , Simon D Rees , Fumihiko Takeuchi , Robin Young , Tin Aung , Abdul Basit , Manickam Chidambaram , Debashish Das , Elin Grundberg , Asa K Hedman , Zafar I Hydrie , Muhammed Islam , Chiea-Chuen Khor , Sudhir Kowlessur , Malene M Kristensen , Samuel Liju , Wei-Yen Lim , David R Matthews , Jianjun Liu , Andrew P Morris , Alexandra C Nica , Janani M Pinidiyapathirage , Inga Prokopenko , Asif Rasheed , Maria Samuel , Nabi Shah , A Samad Shera , Kerrin S Small , Chen Suo , Ananda R Wickremasinghe , Tien Yin Wong , Mingyu Yang , Fan Zhang , DIAGRAM , MuTHER , Goncalo R Abecasis , Anthony H Barnett , Mark Caulfield , Panos Deloukas , Timothy M Frayling , Philippe Froguel , Norihiro Kato , Prasad Katulanda , M Ann Kelly , Junbin Liang , Viswanathan Mohan , Dharambir K Sanghera , James Scott , Mark Seielstad , Paul Z Zimmet , Paul Elliott , Yik Ying Teo , Mark I McCarthy , John Danesh , E Shyong Tai , John C Chambers

Web-based, participant-driven studies yield novel genetic associations for common traits.

PLoS Genet     Nicholas Eriksson , J Michael Macpherson , Joyce Y Tung , Lawrence S Hon , Brian Naughton , Serge Saxonov , Linda Avey , Anne Wojcicki , Itsik Pe'er , Joanna Mountain

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.

PLoS ONE     Tulika Prakash , Vineet K Sharma , Naoki Adati , Ritsuko Ozawa , Naveen Kumar , Yuichiro Nishida , Takayoshi Fujikake , Tadayuki Takeda , Todd D Taylor