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100514823 NLRP3

100514823

NLRP3

NLR family pyrin domain containing 3

protein-coding

Sus scrofa

基因描述

Type Description
Definition NLR family pyrin domain containing 3

研究结论

Date Results Publications
2019-07-27 12:39:00 These studies showed that classical swine fever virus-induced IL-1beta secretion was mediated by NLRP3 and that classical swine fever virus infection could sufficiently activate the assembly of the NLRP3 inflammasome in monocytes. 30013955
2018-11-17 10:15:00 It is an important pattern recognition receptor involved in various inflammatory responses and adjuvant effects upon vaccination. 29770580
2017-05-13 14:30:00 identified six synonymous and six nonsynonymous single-nucleotide polymorphisms (SNPs) in the coding sequence of NLRP3 of six breeds of pigs, including major commercial breeds. Among the nonsynonymous SNPs 27236661
2016-12-17 11:48:00 this study shows that the anti-inflammatory activity of baicalin could be related to the suppression of NLRP3 inflammasome pathway under LPS stimulation 26865578
2014-02-08 11:06:00 dysregulation of SIRT1-AMPK-SREBP and stimulation of NLRP3 inflammasome may contribute to vascular lipid deposition and inflammation in atherosclerosis 23825667

名称对应

Type IDs
Gene
UniProtKB-ID: H2EW08_PIG
UniprotKB: H2EW08
UniParc: UPI000247C529
EMBL: JQ219660, DQIR01022424, DQIR01171064, AEMK02000010
Ensembl: ENSSSCG00000013940
KO: ssc:100514823
Nucleutide sequences
EMBL-CDS: HCZ77899.1, HDB26541.1, AEX66155.1
Ensembl_TRS: ENSSSCT00000054444
Protein sequencees
Ensembl_PRO: ENSSSCP00000037109
RefSeq: XP_020934584.1, XP_020934581.1, NP_001243699.1
Others
UniRef100: UniRef100_H2EW08
UniRef90: UniRef90_A6QLE5
UniRef50: UniRef50_Q96P20
UniGene: Ssc.86156

全选

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研究热度

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