Type | Description |
---|---|
Definition | occludin |
Date | Results | Publications |
---|---|---|
2021-01-02 12:50:00 | A homozygote frameshift mutation in OCLN gene result in Pseudo-TORCH syndrome type I: A case report extending the phenotype with central diabetes insipidus and renal dysfunction. | 32240828 |
2020-10-24 13:56:00 | Progesterone decreases gut permeability through upregulating occludin expression in primary human gut tissues and Caco-2 cells. | 31182728 |
2020-05-30 10:08:00 | miR-424-5p could affect the expression of tight junction proteins, ZO-1 and occludin, via Endophilin-1, and thereby regulate blood brain barrier (BBB) permeability in an BBB model in vitro with Amyloid-beta incubated endothelial cells. | 31375213 |
2020-05-16 11:06:00 | Eighteen residues in the c-terminus are essential for occludin trafficking and hepatitis C virus infection. | 31328852 |
2020-05-16 10:04:00 | OCLN interacted with mitotic spindle regulators, NuMA and RAN, while full-length OCLN loss impaired spindle pole morphology, astral and mitotic microtubule integrity. | 31794381 |
Type | IDs |
---|---|
Synonymous | BLCPMG, PPP1R115, PTORCH1 |
Gene |
UniProtKB-ID:
OCLN_HUMAN,
A8K3T2_HUMAN
UniprotKB:
Q16625,
A8K3T2
UniParc:
UPI0001BE98F6,
UPI0001DDEB9B,
UPI00000341F0,
UPI00015DA70F,
UPI00004230DE,
UPI0000470F95,
UPI0001BEA284,
UPI0001BEA285
EMBL:
GQ402517,
U53823,
AF400626,
BC029886,
FJ786083,
AC145146,
AB451437,
GQ225096,
AF400630,
AF400628,
AF400627,
AF400624,
AK290697,
AB451306,
AF400623,
AC147575,
AF400625,
GQ225097,
FJ786084,
BK001650,
GQ225098,
U49184,
AF400629
Ensembl:
ENSG00000197822
KO:
hsa:100506658
|
Nucleutide sequences |
EMBL-CDS:
AAC50451.1,
BAG70120.1,
ACT83431.1,
BAG70251.1,
AAB00195.1,
ACZ80515.1,
ACT53744.1,
DAA01837.1,
ACT83433.1,
AAH29886.1,
ACT83432.1,
ACT53743.1,
AAL47094.1,
BAF83386.1
Ensembl_TRS:
ENST00000538151,
ENST00000396442,
ENST00000355237
|
Protein sequencees |
Ensembl_PRO:
ENSP00000347379,
ENSP00000379719,
ENSP00000445940
RefSeq:
XP_016864403.1,
NP_001192184.1,
NP_002529.1,
NP_001192183.1,
XP_016864402.1
|
Others |
UniRef100:
UniRef100_A8K3T2,
UniRef100_Q16625
UniRef90:
UniRef90_Q16625
UniRef50:
UniRef50_Q16625
UniGene:
Hs.592605
CCDS:
CCDS54864.1,
CCDS4006.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员