| Type | Description |
|---|---|
| Definition | tumor protein p53 pathway corepressor 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:57:00 | Overexpression of lincRNA p21 promotes FOS expression by binding to miR-221, thereby, inhibiting hippocampal neuron apoptosis in diabetic mice | 31081202 |
| 2020-05-09 11:52:00 | lincRNA-p21 significantly up-regulated in mouse breast cancer cell line 4T1 educated macrophages. LincRNA-p21 knockdown facilitated macrophage polarization into pro-inflammatory M1 in tumor microenvironment, which might be caused by Mdm2 eliciting proteasome-dependent degradation to p53 and activated NF-kappaB and Stat3 pathway. | 32062693 |
| 2019-03-16 11:02:00 | LincRNA-p21 promotes MSC migration and survival capacity through HIF-1a/CXCR4 and CXCR7 pathway under hypoxic preconditioning in vitro. | 30359325 |
| 2018-12-22 11:56:00 | our present results extend the knowledge of lincRNA-p21 and deepen the understanding of the cross talk between lncRNA and profibrogenic TGF-beta signaling cascades in hepatocyte during liver fibrosis. | 28592847 |
| 2018-11-10 11:20:00 | MIF protected MSCs from hypoxia/SDinduced apoptosis by interacting with lincRNAp21, leading to activation of the downstream Wnt/betacatenin signaling pathway and decreased oxidative stress. Thus, treatment with MIF may have important therapeutic implications in improving MSC survival and therapeutic efficiency. | 30015822 |
| Type | IDs |
|---|---|
| Synonymous | Gm16197, linc-p21, lincRNA-p21 |
| Gene | |
| Nucleutide sequences | |
| Protein sequencees | |
| Others |
UniGene:
Mm.438550
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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