| Type | Description |
|---|---|
| Definition | tryptase alpha/beta 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-02-01 11:01:00 | Data indicate that the direct degradation of the integrin subunits by rmMCP-7 is sufficient to initiate angiogenesis. The results demonstrate, for the first time, that mMCP-7 acts in angiogenesis through integrin degradation. | 31013764 |
| 2013-05-25 12:11:00 | Following TNFalpha treatment, increased elastase and tryptase modify the balance between activation and deactivation, elevating active chemerin concentration in adipocyte media and subsequent CMKLR1 activation. | 23227233 |
| 2011-08-30 05:34:00 | Because mMCP-6 and mMCP-7 can compensate for each other in this mouse disease model, the elimination of both tryptases is necessary to reveal the prominent roles of these serine proteases in joint inflammation and destruction. | 18668540 |
| 2011-08-30 05:34:00 | transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia-associated transcription factor | 14527958 |
| 2011-08-30 05:33:00 | TGF-beta stimulates mmcp-7 transcription through the Smad3-Smad4 pathway as well as c-fos induction | 16730810 |
| Type | IDs |
|---|---|
| Synonymous | MMCP-7, Mcp-7, Mcp7, Mcpt7 |
| Gene |
UniProtKB-ID:
TRYB1_MOUSE,
A1Z090_MOUSE
UniprotKB:
Q02844,
A1Z090
UniParc:
UPI000002997B,
UPI000002ADC1
EMBL:
L00654,
EF154453,
GU810527,
L00653,
EU812243,
U42405,
U42406,
GU810534
KO:
mmu:100503895
|
| Nucleutide sequences |
EMBL-CDS:
AAA97874.1,
AAA39993.1,
AAA39992.1,
AAA97875.1,
ADE62296.1,
ACF17728.1,
ADE62306.1,
ABL89215.1
|
| Protein sequencees |
RefSeq:
NP_112464.4
|
| Others |
UniRef100:
UniRef100_Q02844
UniRef90:
UniRef90_Q02844
UniRef50:
UniRef50_P27435
UniGene:
Mm.3301
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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