| Type | Description |
|---|---|
| Definition | RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein |
| Date | Results | Publications |
|---|---|---|
| 2021-02-06 13:53:00 | Upregulation of Rubicon promotes autosis during myocardial ischemia/reperfusion injury. | 32364533 |
| 2020-09-19 16:28:00 | Age-dependent loss of adipose Rubicon promotes metabolic disorders via excess autophagy. | 32811819 |
| 2019-07-06 10:13:00 | Silencing Rubcn, preventing EGFR activity or directly inducing autophagy in retinal pigment epithelial cells by starvation inhibits phagocytic degradation of photoreceptor outer segments. | 28933590 |
| 2019-04-13 11:09:00 | Rubicon role in aging and autophagy. | 30783089 |
| 2017-07-22 10:25:00 | Rubicon specifically interacts with the interferon regulatory factor (IRF) association domain (IAD) of IRF3, and this interaction leads to inhibition of the dimerization of IRF3, which negatively regulates interferon-mediated antiviral response. | 28468885 |
| Type | IDs |
|---|---|
| Synonymous | 1700021K19Rik, 5330403K09, Rubicon, mKIAA0226 |
| Gene |
UniProtKB-ID:
RUBIC_MOUSE
UniprotKB:
Q80U62
UniParc:
UPI0000212E68,
UPI000002714F,
UPI0001D89701,
UPI0000680ADA
EMBL:
AK171583,
AC139244,
AK170223,
BC067390,
BC057307,
AK030368,
AK170002,
AK170312,
BC060601,
AK122221,
AK042428
Ensembl:
ENSMUSG00000035629
KO:
mmu:100502698
|
| Nucleutide sequences |
EMBL-CDS:
AAH60601.1,
BAC26925.1,
BAE41645.1,
AAH67390.1,
BAC65503.1,
BAC31257.1,
BAE41708.1,
AAH57307.1,
BAE41507.1,
BAE42541.1
Ensembl_TRS:
ENSMUST00000115105,
ENSMUST00000040986,
ENSMUST00000089684
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000110757,
ENSMUSP00000087114,
ENSMUSP00000048811
RefSeq:
XP_036015595.1,
XP_036015597.1,
NP_766203.1,
XP_006521715.1,
XP_006521718.1,
XP_036015599.1,
XP_030104756.1,
XP_030104757.1,
XP_006521716.1,
XP_036015598.1,
NP_001186967.1,
NP_001361705.1,
XP_036015596.1
|
| Others |
UniRef100:
UniRef100_Q80U62
UniRef90:
UniRef90_Q80U62
UniRef50:
UniRef50_Q92622
UniGene:
Mm.327319
CCDS:
CCDS28124.1,
CCDS49832.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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