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10048 RANBP9

10048

RANBP9

RAN binding protein 9

protein-coding

Homo sapiens

基因描述

Type Description
Definition RAN binding protein 9

研究结论

Date Results Publications
2019-03-02 12:21:00 the present study provides preclinical and clinical data indicating that lower RANBP9 protein levels might be used, after perspective validation, as a biomarker predictive of response of non-small cell lung cancer to platinum based compounds 30076413
2018-09-29 12:23:00 review provides a complete guide on RanBPM interactors, the physiological role of RanBPM in cellular functions, and potential applications in disease therapeutics. 29723489
2018-05-12 11:16:00 Ran binding protein 9(RanBPM) is a scaffolding protein with a modulatory function that regulates the activities of IFN-stimulated response elements. IFN-lambda1 affects the cellular distribution of RanBPM and stimulates the interaction between RanBPM and interferon, lambda receptor 1(IFN-lambdaR1). Therefore, RanBPM plays a novel role in the IFN-lambda-regulated signaling pathway. 28547582
2018-03-31 10:11:00 Our work shows that RanBPM, together with the CTLH complex, associates with HDAC6 and restricts cell migration through inhibition of HDAC6 activity. This study uncovers a novel function for the CTLH complex and suggests that it could have a tumour suppressive role in restricting HDAC6 oncogenic properties. 28668087
2018-01-06 11:01:00 High RANBPM expression is associated with cancer. 26919101

名称对应

Type IDs
Synonymous BPM-L, BPM90, RANBPM, RanBP7
Gene
UniProtKB-ID: RANB9_HUMAN, A0A024QZW3_HUMAN
UniprotKB: Q96S59, A0A024QZW3
UniParc: UPI0000043C35, UPI0000227E6D, UPI000006ED83
EMBL: Z93020, CH471087, BC063849, AB008515, AK313334, BC052781, AF306510, AL441883, BC019886, AB055311
Ensembl: ENSG00000010017
KO: hsa:10048
Nucleutide sequences
EMBL-CDS: AAK15469.1, AAH52781.1, BAG36138.1, BAA23216.1, BAB62525.1, AAH19886.1, AAH63849.1, EAW55341.1, EAW55345.1
Gene_ORFName: hCG_36756
Ensembl_TRS: ENST00000011619
Protein sequencees
Ensembl_PRO: ENSP00000011619
RefSeq: XP_016865638.1, XP_006715008.1, NP_005484.2, XP_011512507.1
Others
UniRef100: UniRef100_Q96S59
UniRef90: UniRef90_Q96S59
UniRef50: UniRef50_Q96S59
UniGene: Hs.708182
CCDS: CCDS4529.1

全选

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