| Type | Description |
|---|---|
| Definition | SH2 domain containing 3C |
| Date | Results | Publications |
|---|---|---|
| 2012-02-04 10:32:00 | The structure of the NSP3-p130Cas complex reveals that this closed conformation is instrumental for interaction of NSP proteins with a focal adhesion-targeting domain present in Cas proteins. | 22081014 |
| 2010-09-15 22:06:00 | Observational study of gene-disease association. (HuGE Navigator) | 20583170 |
| 2010-01-21 00:00:00 | SH2D3C (SHEP1) is less highly expressed than BCAR3 and NSP1 in breast cancer cells, and the expression patterns suggest differential roles for the three genes during breast cancer progression. | 17270363 |
| 2010-01-21 00:00:00 | NSP3 overexpression did not induce anti-estrogen resistance in breast tumor cell lines. | 17427198 |
| 2010-01-21 00:00:00 | This protein positively regulates T cell receptor-mediated interleukin-2 production by Jurkat cells. | 12486027 |
| Type | IDs |
|---|---|
| Synonymous | CHAT, NSP3, PRO34088, SHEP1 |
| Gene |
UniProtKB-ID:
SH2D3_HUMAN,
B4DG32_HUMAN
UniprotKB:
Q8N5H7,
B4DG32
UniParc:
UPI0000D61911,
UPI0001881B4B,
UPI000006EC87,
UPI00017A6DDE,
UPI00003D44F7,
UPI00000739B5,
UPI0000211878
EMBL:
BC032365,
AF124251,
AY358089,
AK294386,
BC027962,
BX647905,
AL162586,
AY358440,
AK291393,
AL162426,
AK056068
Ensembl:
ENSG00000095370
KO:
hsa:10044
|
| Nucleutide sequences |
EMBL-CDS:
AAQ88456.1,
BAG51614.1,
AAH32365.1,
AAH27962.1,
AAQ89948.1,
CAI46101.1,
AAD28246.1,
BAF84082.1,
BAG57643.1
Gene_ORFName:
UNQ272/PRO309/PRO34088
Ensembl_TRS:
ENST00000373277,
ENST00000373276,
ENST00000429553,
ENST00000629203,
ENST00000420366,
ENST00000314830
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000362373,
ENSP00000317817,
ENSP00000485866,
ENSP00000388536,
ENSP00000362374,
ENSP00000394632
RefSeq:
NP_001239263.1,
NP_001136004.1,
NP_001136006.1,
NP_733745.1,
NP_001136005.1,
NP_005480.2,
NP_001136003.1
|
| Others |
UniRef100:
UniRef100_Q8N5H7,
UniRef100_B4DG32
UniRef90:
UniRef90_B4DG32,
UniRef90_Q8N5H7
UniRef50:
UniRef50_Q9QZS8,
UniRef50_A0A2P4SQJ3
UniGene:
Hs.306412
CCDS:
CCDS48028.1,
CCDS48026.1,
CCDS6878.1,
CCDS6877.1,
CCDS48027.1,
CCDS59145.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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