| Type | Description |
|---|---|
| Definition | target of myb1 membrane trafficking protein |
| Date | Results | Publications |
|---|---|---|
| 2019-10-12 12:36:00 | Study shows that TOM1 regulates neuronal accumulation of amyloid-beta oligomers by FcgammaRIIb2 variant in Alzheimer's Disease (AD). Study provides a molecular mechanism responsible for neuronal uptake of pathogenic Abeta found in AD. | 30185465 |
| 2017-04-22 12:44:00 | This study demonstrated that Tom1 is localized in dystrophic neurites of brain in patient with Alzheimer's disease. | 27206884 |
| 2016-07-30 10:41:00 | Tom1 modulates binding of Tollip to phosphatidylinositol 3-phosphate via a coupled folding and binding mechanism. | 26320582 |
| 2016-04-16 11:54:00 | candidate multiple myeloma risk locus | 26007630 |
| 2016-04-02 11:29:00 | phosphatidylinositol 5-monophosphate (PI5P) enrichment in signaling endosomes prevents endosomal maturation through the recruitment of TOM1, and point to a new function of PI5P in regulating discrete maturation steps in the endosomal system. | 25588840 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
TOM1_HUMAN,
B3KUF5_HUMAN
UniprotKB:
O60784,
B3KUF5
UniParc:
UPI0000137118,
UPI000181CA82,
UPI000181CA83,
UPI000000DB48,
UPI000178E059
EMBL:
AK293694,
AK297827,
Z82244,
AK097066,
CR456595,
BC046151,
AL008635,
AJ006973,
CH471095
Ensembl:
ENSG00000100284
KO:
hsa:10043
|
| Nucleutide sequences |
EMBL-CDS:
BAG57130.1,
EAW60055.1,
CAG30481.1,
CAA07362.1,
AAH46151.1,
BAG60163.1,
BAG53417.1
Ensembl_TRS:
ENST00000425375,
ENST00000411850,
ENST00000449058,
ENST00000447733
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000394466,
ENSP00000398876,
ENSP00000394924,
ENSP00000413697
RefSeq:
XP_011528120.1,
NP_001129204.1,
NP_005479.1,
NP_001129202.1,
NP_001129201.1,
XP_011528122.1,
XP_016884018.1
|
| Others |
UniRef100:
UniRef100_O60784,
UniRef100_B3KUF5
UniRef90:
UniRef90_B3KUF5,
UniRef90_O60784
UniRef50:
UniRef50_O60784,
UniRef50_B3KUF5
UniGene:
Hs.474705
CCDS:
CCDS13913.1,
CCDS46696.1,
CCDS46697.1,
CCDS46698.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员