| Type | Description |
|---|---|
| Definition | microRNA 466 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 12:24:00 | PGM5-AS1 was transcriptionally activated by p53 and it could directly interact with and sequester miR-466 to elevate PTEN expression, thereby inhibiting esophageal squamous cell carcinoma (ESCC) progression. Overall, our data indicate that PGM5-AS1 is a novel tumor suppressor in ESCC and restoration of PGM5-AS1 may be a promising avenue for treatment of ESCC patient. | 31185143 |
| 2019-12-14 12:33:00 | NUS1 was upregulated in IUAs tissues, and the high expression level of NUS1 was positively correlated with the severity of IUAs. NUS1 promoted cell proliferation in vitro. NUS1 overexpression on cell migration and invasion promoted the EMT process in vitro and in vivo. | 31154456 |
| 2019-08-03 11:06:00 | the expression level of miR-466 was significantly downregulated in tumor tissues and cell lines, and its overexpression was able to inhibit cell proliferation and invasion. The tumor-suppressive roles of miR-466 in OS cells were mediated by the silencing of IRS1. | 30816452 |
| 2019-06-29 12:10:00 | miR-466 was downregulated in tumor tissues of prostate carcinoma patients. TUC338 and miR-466 were inversely correlated in tumor tissues. miR-466 overexpression failed to affect TUC338 expression but resulted in reduced rates of cancer cell migration and invasion, and also attenuated the effect of TUC338 overexpression. | 31085276 |
| 2019-01-12 11:48:00 | Study found that miR466 was obviously decreased in hepatocellular carcinoma (HCC) tissues and cell lines. In addition, metadherin (MTDH) was identified as a direct target of miR466 in HCC cells. Furthermore, MTDH was upregulated in HCC tissues, which was inversely correlated with the miR466 level. | 30542714 |
| Type | IDs |
|---|---|
| Synonymous | hsa-mir-466 |