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100422992 MIR3151

100422992

MIR3151

microRNA 3151

ncRNA

Homo sapiens

基因描述

Type Description
Definition microRNA 3151

研究结论

Date Results Publications
2016-11-05 10:16:00 miR-3151 silencing by DNA methylation protected chronic lymphocytic leukemia cells from apoptosis by over-expression of its direct targets MADD and PIK3R2, constitutive activation of MEK/ERK and PI3K/AKT signaling , and over-expression of MCL1. 26517243
2016-04-16 10:40:00 Characterization of TP53 as a downstream effector of miR-3151 provides evidence for a causal link between BRAF mutations and TP53 inactivation 26582795
2016-01-30 12:18:00 miR-3151 emerged as independent prognostic marker in younger patients with acute myeloid leukemia 26430723
2014-12-06 12:48:00 miR-3151 introns within BAALC have roles in driving leukemogenesis by deregulating the TP53 pathway 24736457
2012-09-29 10:20:00 high expression of miR-3151 is an independent prognosticator for poor outcome in cytogenetically normal-AML and affects different outcome end points than its host gene, BAALC 22529287

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Type IDs
Synonymous mir-3151