| Type | Description |
|---|---|
| Definition | chromatin assembly factor 1 subunit A |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 11:51:00 | The histone chaperone Chromatin Assembly Factor 1 (CAF-1), which is recruited to DNA replication forks through its interaction with proliferating cell nuclear antigen (PCNA) for nucleosome assembly, participates in the establishment of H3K27me3-mediated silencing during differentiation. | 31586391 |
| 2019-07-06 12:38:00 | These and other approaches identified the Nucleosome Remodeling Deacetylase (NuRD) and Chromatin Assembly Factor 1 (CAF-1) complexes as necessary for DUX4 repression in human skeletal muscle cells and induced pluripotent stem (iPS) cells.Furthermore, DUX4-induced expression of MBD3L proteins partly relieved this repression in FSHD muscle cells. | 29533181 |
| 2019-04-06 12:43:00 | this study identified a novel oncogenic role of CHAF1A in GC. The upregulation of CHAF1A can promote GC cell growth and predict poor prognosis in GC patients. | 30449701 |
| 2018-08-11 12:16:00 | CHAF1A and PCNA are highly expressed in cervical squamous cell carcinoma and associated with the malignancy | 29382432 |
| 2018-05-26 10:56:00 | Recent work has identified the chromatin assembly factor complex CAF-1 as a potent barrier to cellular reprogramming. In addition, CAF-1 has been implicated in the reversion of pluripotent cells to a totipotent-like state and in various lineage conversion paradigms, suggesting that modulation of CAF-1 levels may endow cells with a developmentally more plastic state. | 28692904 |
| Type | IDs |
|---|---|
| Synonymous | CAF-1, CAF1, CAF1B, CAF1P150, P150 |
| Gene |
UniProtKB-ID:
CAF1A_HUMAN
UniprotKB:
Q13111
UniParc:
UPI00019B21E6,
UPI000CECE35A,
UPI000034E58B
EMBL:
AF190465,
AC011498,
BC052620,
BC067093,
KF459577,
U20979
Ensembl:
ENSG00000167670
KO:
hsa:10036
|
| Nucleutide sequences |
EMBL-CDS:
AAF04291.1,
AAH52620.1,
AAH67093.1,
AAA76736.1
Ensembl_TRS:
ENST00000301280
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000301280
RefSeq:
XP_011525909.1,
NP_005474.2,
XP_011525908.1,
XP_011525907.1
|
| Others |
UniRef100:
UniRef100_Q13111
UniRef90:
UniRef90_Q13111
UniRef50:
UniRef50_Q13111
UniGene:
Hs.79018
CCDS:
CCDS32875.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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