Type | Description |
---|---|
Definition | chromatin assembly factor 1 subunit A |
Date | Results | Publications |
---|---|---|
2020-06-06 11:51:00 | The histone chaperone Chromatin Assembly Factor 1 (CAF-1), which is recruited to DNA replication forks through its interaction with proliferating cell nuclear antigen (PCNA) for nucleosome assembly, participates in the establishment of H3K27me3-mediated silencing during differentiation. | 31586391 |
2019-07-06 12:38:00 | These and other approaches identified the Nucleosome Remodeling Deacetylase (NuRD) and Chromatin Assembly Factor 1 (CAF-1) complexes as necessary for DUX4 repression in human skeletal muscle cells and induced pluripotent stem (iPS) cells.Furthermore, DUX4-induced expression of MBD3L proteins partly relieved this repression in FSHD muscle cells. | 29533181 |
2019-04-06 12:43:00 | this study identified a novel oncogenic role of CHAF1A in GC. The upregulation of CHAF1A can promote GC cell growth and predict poor prognosis in GC patients. | 30449701 |
2018-08-11 12:16:00 | CHAF1A and PCNA are highly expressed in cervical squamous cell carcinoma and associated with the malignancy | 29382432 |
2018-05-26 10:56:00 | Recent work has identified the chromatin assembly factor complex CAF-1 as a potent barrier to cellular reprogramming. In addition, CAF-1 has been implicated in the reversion of pluripotent cells to a totipotent-like state and in various lineage conversion paradigms, suggesting that modulation of CAF-1 levels may endow cells with a developmentally more plastic state. | 28692904 |
Type | IDs |
---|---|
Synonymous | CAF-1, CAF1, CAF1B, CAF1P150, P150 |
Gene |
UniProtKB-ID:
CAF1A_HUMAN
UniprotKB:
Q13111
UniParc:
UPI00019B21E6,
UPI000CECE35A,
UPI000034E58B
EMBL:
AF190465,
AC011498,
BC052620,
BC067093,
KF459577,
U20979
Ensembl:
ENSG00000167670
KO:
hsa:10036
|
Nucleutide sequences |
EMBL-CDS:
AAF04291.1,
AAH52620.1,
AAH67093.1,
AAA76736.1
Ensembl_TRS:
ENST00000301280
|
Protein sequencees |
Ensembl_PRO:
ENSP00000301280
RefSeq:
XP_011525909.1,
NP_005474.2,
XP_011525908.1,
XP_011525907.1
|
Others |
UniRef100:
UniRef100_Q13111
UniRef90:
UniRef90_Q13111
UniRef50:
UniRef50_Q13111
UniGene:
Hs.79018
CCDS:
CCDS32875.1
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
暂无数据
排名 | 科研单位 | 文献 |
---|---|---|
{{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
排名 | 研究人员 | 文献 |
---|---|---|
{{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员