| Type | Description |
|---|---|
| Definition | protein phosphatase 1, regulatory subunit 8 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-13 13:15:00 | Phosphatase Regulator NIPP1 Restrains Chemokine-Driven Skin Inflammation. | 31972250 |
| 2019-07-13 11:54:00 | We conclude that NIPP1 is essential for mammalian spermatogenesis because it is indispensable for the proliferation and survival of progenitor germ cells, including (un)differentiated spermatogonia. | 29042623 |
| 2019-06-29 11:28:00 | NIPP1 deletion abrogated PP1-mediated EZH2 dephosphorylation at two cyclin-dependent kinase sites (Thr-345/487), thereby generating hyperphosphorylated EZH2, which is a substrate for proteolytic degradation. | 30305391 |
| 2017-12-16 10:53:00 | NIPP1 does not regulate the proliferation of hepatocytes but is a suppressor of biliary epithelial cell proliferation, including progenitor cells, in the adult liver. | 27068806 |
| 2016-05-07 10:29:00 | activation of the by advanced glycation end products or other ligands suppresses NIPP1 expression in diabetic nephropathy, contributes to podocyte hypertrophy, and glomerular inflammation | 24476693 |
| Type | IDs |
|---|---|
| Synonymous | 6330548N22Rik, AU044684, NIPP1 |
| Gene |
UniProtKB-ID:
PP1R8_MOUSE,
A2ADR8_MOUSE
UniprotKB:
Q8R3G1,
A2ADR8
UniParc:
UPI000059E14B,
UPI000002301D
EMBL:
BC025479,
AK032022,
AL671190
Ensembl:
ENSMUSG00000028882
KO:
mmu:100336
|
| Nucleutide sequences |
EMBL-CDS:
AAH25479.1,
BAC27653.1
Ensembl_TRS:
ENSMUST00000030702,
ENSMUST00000105919
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030702,
ENSMUSP00000101539
RefSeq:
NP_001342127.1,
NP_001342128.1,
NP_001277654.1,
NP_666266.1
|
| Others |
UniRef100:
UniRef100_A2ADR8,
UniRef100_Q8R3G1
UniRef90:
UniRef90_Q12972
UniRef50:
UniRef50_Q12972
UniGene:
Mm.105230
CCDS:
CCDS18736.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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