| Type | Description |
|---|---|
| Definition | WASH complex subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-05-25 12:19:00 | In this study, we uncover an alternative role for the ESCRT-0 component hepatocyte growth factor-regulated tyrosine kinase substrate (HRS) in promoting the constitutive recycling of transmembrane proteins. We find that endosomal localization of the actin nucleating factor Wiscott-Aldrich syndrome protein and SCAR homologue (WASH) requires HRS, which occupies adjacent endosomal subdomains | 29891722 |
| 2018-11-24 12:05:00 | WASH-mediated AHR expression has a critical function in the maintenance of NKp46+ innate lymphoid cells | 28589939 |
| 2017-11-18 10:48:00 | Its mutation is not found in a cohort of German patients with sporadic amyotrophic lateral sclerosis and frontotemporal lobar degeneration comorbidity. | 28551275 |
| 2017-10-28 13:40:00 | WASH has a pivotal role for regulation of NK cell cytotoxicity through Lck-mediated Y141 tyrosine phosphorylation. | 27441653 |
| 2017-08-12 10:56:00 | ANKRD50 simultaneously engages multiple parts of the SNX27-retromer-WASH complex machinery in a direct and co-operative interaction network that is needed to efficiently recycle the nutrient transporters. | 27909246 |
| Type | IDs |
|---|---|
| Synonymous | FAM39E, WASH, WASH1 |
| Gene |
UniProtKB-ID:
WASH1_HUMAN
UniprotKB:
A8K0Z3
UniParc:
UPI0000251DC1
EMBL:
AL928970,
AK289708
Ensembl:
ENSG00000181404
KO:
hsa:100287171
|
| Nucleutide sequences |
EMBL-CDS:
BAF82397.1
Ensembl_TRS:
ENST00000442898
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000485627
RefSeq:
XP_024303138.1,
XP_011515965.1,
XP_024303137.1,
XP_016869659.1,
XP_011515968.1,
XP_011515961.1,
XP_016869660.1,
NP_001365019.1,
XP_011515967.1,
XP_011515966.1,
XP_011515962.1,
XP_011515964.1,
NP_878908.4,
XP_016869662.1,
XP_016869661.1,
XP_016869658.1
|
| Others |
UniRef100:
UniRef100_A8K0Z3
UniRef90:
UniRef90_A8K0Z3
UniRef50:
UniRef50_A8K0Z3
UniGene:
Hs.446466,
Hs.459573,
Hs.461200,
Hs.521961,
Hs.585931,
Hs.709408
CCDS:
CCDS78375.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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