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10022 INSL5

10022

INSL5

insulin like 5

protein-coding

Homo sapiens

基因描述

Type Description
Definition insulin like 5

研究结论

Date Results Publications
2019-09-14 10:42:00 This study provides novel insights into possible autocrine/paracrine roles of INSL5 in the intestinal tract. 29535183
2019-07-13 12:47:00 High serum INLS5 levels are associated with metabolic diseases in women with polycystic ovary syndrome. 29956214
2019-03-23 10:29:00 The R27S (B5Ser) mutant variant of INSL5 was evaluated as a potential antagonist of the native RXFP4 receptor, yet was found to match the potency and maximal efficacy to the native hormone. This informs that the R27S phenotype is not directly linked to the receptor activity of the peptide, but likely affects endogenous hormone production or secretion. 29466617
2018-09-08 10:39:00 Mass spectral analysis of purified enteroendocrine cells and tissue homogenates identified the exact sequence of A and B chains of INSL5 endogenously expressed in L-cells. 28857318
2017-05-20 10:12:00 analysis of the interaction mechanism of INSL5 with its receptor RXFP4 28274616

名称对应

Type IDs
Synonymous PRO182, UNQ156
Gene
UniProtKB-ID: INSL5_HUMAN
UniprotKB: Q9Y5Q6
UniParc: UPI000013E991
EMBL: AF133816, AL354978, BC101648, AY359030, BC101646
Ensembl: ENSG00000172410
KO: hsa:10022
Nucleutide sequences
EMBL-CDS: AAI01649.1, AAI01647.1, AAQ89389.1, AAD29686.1
Gene_ORFName: UNQ156/PRO182
Ensembl_TRS: ENST00000304526
Protein sequencees
Ensembl_PRO: ENSP00000302724
RefSeq: NP_005469.2
Others
UniRef100: UniRef100_Q9Y5Q6
UniRef90: UniRef90_Q9Y5Q6
UniRef50: UniRef50_Q9Y5Q6
UniGene: Hs.251380
CCDS: CCDS634.1

全选

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研究热度

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