| Type | Description |
|---|---|
| Definition | hyperpolarization activated cyclic nucleotide gated potassium channel 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:17:00 | [The effects of PDK1-Akt signaling pathway intervention on cardiomyocyte HCN4 ion channels]. | 33210868 |
| 2020-05-30 10:25:00 | HCN4-P883R may increase ectopic trigger and maintenance of atrial fibrillation by shifting the activation voltage. | 31481236 |
| 2020-01-04 11:05:00 | We report the in vitro functional characterization of four rare variants of uncertain significance in HCN4, identified through testing a cohort of 296 sudden unexpected natural deaths | 30578647 |
| 2019-12-21 11:24:00 | HCN4 gene polymorphisms and lone atrial fibrillation risk | 31315459 |
| 2019-08-24 11:12:00 | One missense heterozygous variant c.1578C>T (Ala195Val) and four synonymous heterozygous variants c.1552C>T, c.2833C>T, c.3823C>T, and c.4189C>A were discovered in the Sudden unexplained nocturnal death syndrome cases | 30452770 |
| Type | IDs |
|---|---|
| Synonymous | SSS2 |
| Gene |
UniProtKB-ID:
HCN4_HUMAN
UniprotKB:
Q9Y3Q4
UniParc:
UPI000003FFB5
EMBL:
AJ238850,
AJ132429
Ensembl:
ENSG00000138622
KO:
hsa:10021
|
| Nucleutide sequences |
EMBL-CDS:
CAB52754.1,
CAB42604.1
Ensembl_TRS:
ENST00000261917
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000261917
RefSeq:
XP_011519450.1,
NP_005468.1
|
| Others |
UniRef100:
UniRef100_Q9Y3Q4
UniRef90:
UniRef90_Q9Y3Q4
UniRef50:
UniRef50_Q9Y3Q4
UniGene:
Hs.86941
CCDS:
CCDS10248.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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