| Type | Description |
|---|---|
| Definition | ADP-ribosylhydrolase like 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-05-16 10:56:00 | Arh3-deficient mouse showed vulnerability to parthanatos. Arh3-/- fibroblasts demonstrated the failure of normal poly(ADP-ribose) (PAR) degradation in the nucleus and cytoplasm resulted in apoptosis-inducing factor-mediated DNA fragmentation. Data indicate that Arh3 is a PAR-degrading enzyme responsible for the regulation of PAR metabolism under conditions of oxidative stress both in vivo and in vitro. | 30830864 |
| 2012-07-14 10:33:00 | ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose) glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose). | 22433848 |
| 2010-01-21 00:00:00 | structural comparison of mouse ADP-ribosylhydrolase 3 with its human orthologue shows a high degree of structural similarity | 18323597 |
| 2010-01-21 00:00:00 | ARH3 has poly(ADP-ribose) glycohydrolase activity but is structurally unrelated to poly(ADP-ribose) glycohydrolase | 16278211 |
| Type | IDs |
|---|---|
| Synonymous | AI836109, Arh3 |
| Gene |
UniProtKB-ID:
ADPRS_MOUSE
UniprotKB:
Q8CG72
UniParc:
UPI000000B75E,
UPI00000E8F0B
EMBL:
BC023177,
AL606976,
AJ427296,
AK143583,
BC045203,
BC010639,
AK147034,
AK169070,
AK171780
Ensembl:
ENSMUSG00000042558
KO:
mmu:100206
|
| Nucleutide sequences |
EMBL-CDS:
AAH23177.2,
BAE40857.1,
AAH45203.1,
AAH10639.1,
BAE27626.1,
BAE42660.1,
BAE25451.1,
CAD20317.1
Ensembl_TRS:
ENSMUST00000102617
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000099677
RefSeq:
NP_598644.1
|
| Others |
UniRef100:
UniRef100_Q8CG72
UniRef90:
UniRef90_Q8CG72
UniRef50:
UniRef50_Q8CG72
UniGene:
Mm.11285
CCDS:
CCDS18650.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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