BCL2L11 - BCL2 like 11-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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10018 BCL2L11

基因描述

Type	Description
Definition	BCL2 like 11

研究结论

Date	Results	Publications
2021-04-17 13:11:00	Glucocorticoids can induce BIM to trigger apoptosis in the absence of BAX and BAK1.	32513923
2021-04-03 13:32:00	The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils.	32844279
2021-03-13 13:14:00	miR-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of PTEN and BCL2L11 and modulation of AKT/mTOR signaling.	31960416
2021-03-06 13:26:00	Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non-small cell lung cancer.	33103296
2021-02-27 13:49:00	hsa-miR-20b-5p and hsa-miR-363-3p Affect Expression of PTEN and BIM and Modulate Survival of T-ALL Cells In Vitro.	32380791

名称对应

Type	IDs
Synonymous	BAM, BIM, BOD
Gene	UniProtKB-ID: B2L11_HUMAN, A0A0C4DH20_HUMAN, A0A0A0MRE7_HUMAN UniprotKB: O43521, A0A0C4DH20, A0A0A0MRE7 UniParc: UPI000181EEE6, UPI00001D9607, UPI000037658F, UPI000022B93E, UPI0000DC39F7, UPI000255FF32, UPI000002A4CB, UPI00001D9609, UPI000181EEE7, UPI00000707F1, UPI0000DC39F6, UPI0001F936D4, UPI000007019E, UPI0000033ABA, UPI00000739DB, UPI00001BE2AB, UPI0000070070, UPI00001D9608, UPI000255FF33, UPI000006FC15, UPI00001E0969, UPI000255FF31 EMBL: AB071198, AC096670, AF032457, AB071199, AB071197, AK291269, AY352518, AY423442, AY423443, AY305715, AK290377, AY423441, CH471237, AB071195, DQ849202, AB071200, AF032458, AB071196, DQ849200, BC033694, DQ849201, AY305714, AY428962 Ensembl: ENSG00000153094 KO: hsa:10018
Nucleutide sequences	EMBL-CDS: BAF83958.1, BAB78589.1, AAQ82546.1, AAQ99150.1, AAR06908.1, AAY14797.1, AAC39594.1, AAH33694.1, EAW50370.1, EAW50365.1, ABI13591.1, AAQ99148.1, EAW50373.1, EAW50372.1, ABI13590.1, BAB78591.1, ABI13589.1, BAB78594.1, AAQ82547.1, BAB78592.1, EAW50369.1, AAC39593.1, EAW50367.1, BAB78590.1, EAW50371.1, EAW50374.1, BAB78593.1, BAF83066.1, AAQ99149.1, AAQ62569.1 Ensembl_TRS: ENST00000308659, ENST00000621302, ENST00000615946, ENST00000433098, ENST00000439718, ENST00000337565, ENST00000431217, ENST00000393256, ENST00000610735, ENST00000405953, ENST00000622509, ENST00000452231, ENST00000436733, ENST00000622612, ENST00000620862, ENST00000619294, ENST00000437029, ENST00000415458, ENST00000361493, ENST00000357757
Protein sequencees	Ensembl_PRO: ENSP00000401662, ENSP00000479714, ENSP00000481423, ENSP00000384641, ENSP00000484360, ENSP00000391292, ENSP00000393781, ENSP00000481652, ENSP00000411137, ENSP00000338374, ENSP00000482175, ENSP00000412892, ENSP00000403727, ENSP00000394640, ENSP00000478133, ENSP00000376943, ENSP00000309226, ENSP00000481030, ENSP00000354879, ENSP00000350398 RefSeq: XP_005263608.1, NP_996885.1, XP_005263618.1, NP_619533.1, NP_996886.1, NP_001191037.1, NP_001191035.1, XP_005263613.1, XP_005263607.1, NP_001191036.1, NP_619531.1, NP_001191040.1, XP_005263611.1, NP_001191038.1, XP_005263612.1, XP_005263609.1, NP_619530.1, NP_619532.1, NP_001191041.1, NP_006529.1, XP_005263616.1, XP_016858591.1, XP_011508766.1, NP_001191042.1, XP_011508763.1, NP_619527.1, NP_619528.1, XP_016858590.1, XP_005263614.1, XP_005263610.1, NP_001191039.1, NP_619529.1
Others	UniRef100: UniRef100_A0A0A0MRE7, UniRef100_O43521-12, UniRef100_O43521 UniRef90: UniRef90_A0A2I3MT80, UniRef90_O43521, UniRef90_O43521-12 UniRef50: UniRef50_A0A2I3MT80, UniRef50_O43521, UniRef50_O43521-2 UniGene: Hs.469658, Hs.737004 CCDS: CCDS74560.1, CCDS74561.1, CCDS2089.1, CCDS2092.1, CCDS56131.1, CCDS56134.1, CCDS56136.1, CCDS42731.1, CCDS56135.1, CCDS56133.1, CCDS56132.1

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mRNA

Protein

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Description

Refseq

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全选

Pubmed编号	文献信息	发表日期	相关基因
32844279	The pro-apoptotic domain of BIM protein forms toxic amyloid fibrils. Cell Mol Life Sci Ravit Malishev , Shani Ben-Zichri , Ofek Oren , Nitzan Shauloff , Tal Peretz , Ran Taube , Niv Papo , Raz Jelinek	2021-03-01	-
33103296	Clinical significance of BIM deletion polymorphism in chemoradiotherapy for non-small cell lung cancer. Cancer Sci Yu Wakabayashi , Takeshi Masuda , Kazunori Fujitaka , Taku Nakashima , Joe Okumoto , Kiyofumi Shimoji , Yoshifumi Nishimura , Kakuhiro Yamaguchi , Shinjiro Sakamoto , Yasushi Horimasu , Shintaro Miyamoto , Hiroshi Iwamoto , Shinichiro Ohshimo , Hironobu Hamada , Noboru Hattori	2021-01-01	-
31960416	miR-885 mediated cardioprotection against hypoxia/reoxygenation-induced apoptosis in human cardiomyocytes via inhibition of PTEN and BCL2L11 and modulation of AKT/mTOR signaling. J Cell Physiol Xin Meng , Lijun Mei , Chedong Zhao , Wei Chen , Ning Zhang	2020-11-01	-
32651234	The chaperone Hsp70 is a BH3 receptor activated by the pro-apoptotic Bim to stabilize anti-apoptotic clients. J Biol Chem Zongwei Guo , Ting Song , Ziqian Wang , Donghai Lin , Keke Cao , Peng Liu , Yingang Feng , Xiaodong Zhang , Peiran Wang , Fangkui Yin , Jian Dai , Sheng Zhou , Zhichao Zhang	2020-09-11	-
32814053	Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains. Cell Rep Christian Haenig , Nir Atias , Alexander K Taylor , Arnon Mazza , Martin H Schaefer , Jenny Russ , Sean-Patrick Riechers , Shushant Jain , Maura Coughlin , Jean-Fred Fontaine , Brian D Freibaum , Lydia Brusendorf , Martina Zenkner , Pablo Porras , Martin Stroedicke , Sigrid Schnoegl , Kristin Arnsburg , Annett Boeddrich , Lucia Pigazzini , Peter Heutink , J Paul Taylor , Janine Kirstein , Miguel A Andrade-Navarro , Roded Sharan , Erich E Wanker	2020-08-18	-
32600444	PRKCQ inhibition enhances chemosensitivity of triple-negative breast cancer by regulating Bim. Breast Cancer Res Jessica H Byerly , Elisa R Port , Hanna Y Irie	2020-06-29	-
32591507	Spermine synthase and MYC cooperate to maintain colorectal cancer cell survival by repressing Bim expression. Nat Commun Yubin Guo , Qing Ye , Pan Deng , Yanan Cao , Daheng He , Zhaohe Zhou , Chi Wang , Yekaterina Y Zaytseva , Charles E Schwartz , Eun Y Lee , B Mark Evers , Andrew J Morris , Side Liu , Qing-Bai She	2020-06-26	-
32513923	Glucocorticoids can induce BIM to trigger apoptosis in the absence of BAX and BAK1. Cell Death Dis Li Dong , David L Vaux	2020-06-08	-
32247610	EMT-inducing transcription factor ZEB1-associated resistance to the BCL-2/BCL-X_L inhibitor is overcome by BIM upregulation in ovarian clear cell carcinoma cells. Biochem Biophys Res Commun Akane Inoue-Yamauchi , Hideaki Oda	2020-06-04	-
32380791	hsa-miR-20b-5p and hsa-miR-363-3p Affect Expression of PTEN and BIM Tumor Suppressor Genes and Modulate Survival of T-ALL Cells In Vitro. Cells Monika Drobna , BronisÅawa SzarzyÅska , Roman Jaksik , Åukasz SÄdek , Anna Kuchmiy , Tom Taghon , Pieter Van Vlierberghe , Tomasz SzczepaÅski , MichaÅ Witt , MaÅgorzata Dawidowska	2020-05-05	-

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