CBD103 - beta-defensin 103-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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100170103 CBD103

基因描述

Type	Description
Definition	beta-defensin 103

研究结论

Date	Results	Publications
2013-06-22 11:31:00	The results of this study suggest that differential expression of ASIP determine pigment-type switching in a MC1R and K allele-dependent manner in dogs.	22524303
2012-09-01 11:02:00	the similarities of CBD103 and its human ortholog reported here support the notion that the domestic dog may serve as a valuable model for studying beta-defensin biology in the skin.	22261569
2011-12-03 11:23:00	2 key mutations in the MC1R gene and the CBD103 gene are associated with the phenotypic discriminations among brindle, red/sesame, and white coats.	21321476
2010-01-21 00:00:00	study identifies the K locus as beta-defensin 103 (CBD103) and shows that its protein product binds with high affinity to the melanocortin 1 receptor and has a simple and strong effect on pigment type-switching [CBD103]	17947548
2010-01-21 00:00:00	Data show thatc ontrary to cBD1, expression of cBD103 was slightly (2-fold) downregulated in skin of atopic dogs.	19576634

名称对应

Type	IDs
Gene	UniProtKB-ID: Q30KV0_CANLF UniprotKB: Q30KV0 UniParc: UPI00005E4406 EMBL: KC332836, KC332773, KC332750, KC332787, KC332754, DQ011972, KC332804, KC332712, KC332798, KC332867, KC332772, KC332725, KC332796, KC332877, KC332862, KC332846, KC332758, KC332721, KC332726, KC332718, KC332882, KC332692, KC332749, KC332832, KC332848, KC332817, KC332702, KC332708, KC332823, KC332697, KC332790, KC332854, KC332803, KC332814, KC332822, KC332873, KC332794, KC332841, KC332698, KC332771, KC332719, KC332764, KC332703, KC332734, KC332871, KC332690, KC332863, KC332700, KC332880, KC332731, KC332701, KC332707, KC332850, KC332833, KC332699, KC332870, KC332766, KC332881, KC332866, KC332762, KC332805, KC332744, KC332844, KC332830, KC332760, KC332874, KC332765, KC332777, KC332852, KC332774, KC332775, KC332747, KC332835, KC332740, KC332860, KC332845, KC332691, KC332806, KC332720, KC332780, KC332801, KC332781, KC332716, KC332728, KC332864, KC332694, KC332875, KC332786, KC332869, KC332839, KC332705, KC332879, KC332743, KC332785, KC332791, KC332853, KC332695, KC332751, KC332746, KC332825, KC332741, KC332824, KC332753, KC332827, KC332717, KC332752, KC332729, KC332811, KC332838, KC332868, KC332788, KC332793, KC332842, KC332687, KC332809, KC332872, KC332784, KC332730, KC332779, KC332714, KC332761, KC332709, KC332727, KC332696, KC332808, KC332828, KC332724, KC332819, KC332732, KC332735, KC332834, KC332857, KC332722, KC332738, KC332807, KC332797, KC332810, KC332855, KC332849, KC332768, KC332733, KC332769, KC332689, KC332820, KC332778, KC332815, KC332742, KC332776, KC332757, KC332745, KC332858, KC332831, KC332789, KC332737, KC332840, KC332756, KC332843, KC332688, KC332847, KC332865, KC332812, KC332713, KC332792, KC332711, KC332710, KC332770, KC332816, KC332715, KC332782, KC332851, KC332800, KC332795, KC332837, KC332736, KC332748, KC332759, KC332878, KC332783, KC332876, KC332818, KC332799, KC332813, KC332723, KC332706, KC332859, KC332739, KC332704, KC332826, KC332755, KC332821, KC332693, KC332763, KC332856, KC332767, KC332861, KC332802, KC332829 KO: cfa:100170103
Nucleutide sequences	EMBL-CDS: AGG12409.1, AGG12276.1, AGG12321.1, AGG12380.1, AGG12370.1, AGG12278.1, AGG12332.1, AGG12404.1, AGG12413.1, AGG12347.1, AGG12448.1, AGG12318.1, AGG12288.1, AGG12322.1, AGG12440.1, AGG12341.1, AGG12372.1, AGG12396.1, AGG12421.1, AGG12292.1, AGG12346.1, AGG12313.1, AGG12311.1, AGG12350.1, AGG12273.1, AGG12330.1, AGG12400.1, AGG12352.1, AGG12443.1, AGG12434.1, AGG12289.1, AGG12384.1, AGG12376.1, AGG12310.1, AGG12267.1, AGG12337.1, AGG12281.1, AGG12351.1, AGG12398.1, AGG12338.1, AGG12277.1, AGG12412.1, AGG12301.1, AGG12363.1, AGG12360.1, AGG12300.1, AGG12405.1, AGG12414.1, AGG12264.1, AGG12333.1, AGG12450.1, AGG12344.1, AGG12356.1, AGG12320.1, AGG12286.1, AGG12357.1, AGG12331.1, AGG12445.1, AGG12342.1, AGG12458.1, AGG12307.1, AGG12294.1, AGG12381.1, AGG12456.1, AGG12266.1, AGG12432.1, AGG12299.1, AGG12454.1, AGG12293.1, AGG12327.1, AGG12271.1, AGG12279.1, AGG12290.1, AGG12455.1, AGG12395.1, AGG12385.1, AGG12349.1, AGG12362.1, AGG12325.1, AGG12329.1, AGG12379.1, AGG12378.1, AGG12287.1, AGG12418.1, AGG12306.1, AGG12437.1, AGG12417.1, AGG12274.1, AGG12304.1, AGG12272.1, AGG12297.1, AGG12425.1, AGG12391.1, AGG12438.1, AGG12291.1, AGG12302.1, AGG12388.1, AGG12348.1, AGG12416.1, AGG12355.1, AGG12392.1, AGG12433.1, AGG12444.1, AGG12419.1, AGG12377.1, AGG12295.1, AGG12449.1, AGG12415.1, AGG12336.1, AGG12270.1, AGG12361.1, AGG12459.1, AGG12451.1, AGG12408.1, AGG12428.1, AGG12383.1, AGG12429.1, AGG12374.1, AGG12427.1, AGG12334.1, AGG12399.1, AGG12394.1, AGG12359.1, AGG12422.1, AGG12365.1, AGG12275.1, AGG12340.1, AGG12424.1, AGG12283.1, AGG12269.1, AGG12447.1, AGG12442.1, AGG12431.1, AGG12305.1, AGG12326.1, AGG12423.1, AGG12324.1, AGG12298.1, AGG12303.1, AGG12441.1, AGG12373.1, AGG12316.1, AGG12312.1, AGG12364.1, AGG12420.1, AGG12368.1, AGG12407.1, AGG12435.1, AGG12411.1, AGG12367.1, AGG12317.1, AGG12268.1, AGG12390.1, AGG12353.1, AGG12343.1, AGG12335.1, AAY59710.1, AGG12430.1, AGG12371.1, AGG12386.1, AGG12339.1, AGG12406.1, AGG12296.1, AGG12358.1, AGG12387.1, AGG12366.1, AGG12354.1, AGG12453.1, AGG12426.1, AGG12314.1, AGG12397.1, AGG12436.1, AGG12345.1, AGG12401.1, AGG12402.1, AGG12328.1, AGG12282.1, AGG12285.1, AGG12452.1, AGG12382.1, AGG12319.1, AGG12309.1, AGG12389.1, AGG12323.1, AGG12403.1, AGG12265.1, AGG12369.1, AGG12446.1, AGG12315.1, AGG12439.1, AGG12308.1, AGG12280.1, AGG12284.1, AGG12393.1, AGG12375.1, AGG12410.1, AGG12457.1
Protein sequencees	RefSeq: NP_001123452.1
Others	UniRef100: UniRef100_J9NU53 UniRef90: UniRef90_J9NU53 UniRef50: UniRef50_S9YEN8 UniGene: Cfa.24595

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
22524303	Characterization of different 5'-untranslated exons of the ASIP gene in black-and-tan Doberman Pinscher and brindle Boxer dogs. Anim. Genet. Roberta Ciampolini , Francesca Cecchi , Andrea Spaterna , Assunta Bramante , Sylvia M Bardet , Ahmad Oulmouden	2013-02-01	CBD103, MC1R, ASIP
23424634	Signature of balancing selection at the MC1R gene in Kunming dog populations. PLoS ONE Guo-dong Wang , Lu-guang Cheng , Ruo-xi Fan , David M Irwin , Shu-sheng Tang , Jian-guo Peng , Ya-ping Zhang	2013-01-01	CBD103, MC1R
22261569	Activity, expression and genetic variation of canine Î²-defensin 103: a multifunctional antimicrobial peptide in the skin of domestic dogs. J Innate Immun Brian C Leonard , Stanley L Marks , Catherine A Outerbridge , Verena K Affolter , Anchasa Kananurak , Amy Young , Peter F Moore , Danika L Bannasch , Charles L Bevins	2012-01-01	CBD103
21321476	Mutations in the melanocortin 1 receptor, Î²-defensin103 and agouti signaling protein genes, and their association with coat color phenotypes in Akita-inu dogs. J. Vet. Med. Sci. Mieko Oguro-Okano , Mioko Honda , Kaoru Yamazaki , Keiju Okano	2011-07-01	-
19576634	Altered cutaneous expression of beta-defensins in dogs with atopic dermatitis. Mol. Immunol. Catharina M M van Damme , Ton Willemse , Albert van Dijk , Henk P Haagsman , Edwin J A Veldhuizen	2009-08-01	CBD103, DEFB1
17947548	A -defensin mutation causes black coat color in domestic dogs. Science Sophie I Candille , Christopher B Kaelin , Bruce M Cattanach , Bin Yu , Darren A Thompson , Matthew A Nix , Julie A Kerns , Sheila M Schmutz , Glenn L Millhauser , Gregory S Barsh	2007-11-30	Mc1r, CBD103, MC1R
16033865	Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. Physiol. Genomics Amar A Patil , Yibin Cai , Yongming Sang , Frank Blecha , Guolong Zhang	2005-09-21	Gm6040, Gm15056, Gm17416, Defb19, Defb36, Defb20, Defb50, Defb21, Defb48, Defb45, Defb22, Defb28, Spag11b, Defb46, Defb42, Defb23, Defa-ps12, Defb33, Defb44-ps, Gm21944, Defa-ps13, Defb26, Defb43, Defb25, Defb18, Gm15386, Defb47, Defb30, Defb41, Spag11a, Defb22, Defb52, Defb29, Defb51, Defb23, Defb16-ps, Defb3, Defb5, Defb13, Defb14, Defb28, Defb26, Defb11, Defb2, Defb24, Defb9, Defb19, Defb10, Defb21, Defb40, Defb50, Defb36, Defb20, Defb27, Defb12, Defb25, Defb15, Defb39, Defb33, Defb41, Defb43, Defb44, Defb49, Defb18, Defb30, Defb42, Defb17, Defb4, Defb37, Defb38, Spag11b, DEFB107A, LOC100170034, DEFB110, DEFB117, DEFB103A, DEFB126, DEFB104, DEFB106A, DEFB105A, DEFB108P, DEFB134, DEFB136, DEFB135, DEFB133, DEFB114, DEFB113, DEFB112, DEFB115, DEFB118, DEFB123, DEFB124, DEFB131, DEFB127, DEFB129, DEFB132, DEFB116, DEFB119, DEFB121

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