| Type | Description |
|---|---|
| Definition | programmed cell death 6 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-21 13:16:00 | ALG-2 couples T cell activation and apoptosis by regulating proteasome activity and influencing MCL1 stability. | 31919392 |
| 2019-11-23 10:38:00 | The low expression of miR-124 can promote the proliferation as well as migration of esophageal cancer cells and inhibit cell apoptosis. The mechanism may be that miR-124 can regulate the expression of PDCD6. | 31128039 |
| 2019-02-02 12:26:00 | ALG-2 is predominantly localized to a specialized region of the endoplasmic reticulum (ER), called the ER exit site (ERES), through its interaction with Sec31A. Sec31A is an outer coat protein of coat protein complex II (COPII) and is recruited from the cytosol to the ERES to form COPII-coated transport vesicles | 30259798 |
| 2018-10-06 11:26:00 | Up-regulation of miR-20a by HPV16 E6 exerted growth-promoting effects by targeting PDCD6 in cervical carcinoma cells. | 29710555 |
| 2018-07-28 11:38:00 | the t(5;21)(p15;q22) translocation could be identified only when what had seemed like a del(21)(qq) in G-banded preparations was examined using FISH and RNA-sequencing directed at finding out what lay behind the 21q-. | 29672642 |
| Type | IDs |
|---|---|
| Synonymous | ALG-2, ALG2, PEF1B |
| Gene |
UniProtKB-ID:
PDCD6_HUMAN,
Q53FC3_HUMAN,
A0A024QZ42_HUMAN,
A0A087WZ38_HUMAN
UniprotKB:
O75340,
Q53FC3,
A0A024QZ42,
A0A087WZ38
UniParc:
UPI0001D3B0CD,
UPI000050A97E,
UPI00005EE22B,
UPI00001313D9,
UPI0000EE80E1,
UPI000020BE8B
EMBL:
AK315370,
AC010442,
CH471235,
AC021087,
BC012384,
CB991882,
AC118458,
BC110291,
BC106706,
U58773,
AK223366,
BT020072,
AF035606
Ensembl:
ENSG00000249915
KO:
hsa:10016
|
| Nucleutide sequences |
EMBL-CDS:
AAI06707.1,
AAI10292.1,
AAC27697.1,
BAG37763.1,
EAW50991.1,
AAH12384.1,
AAF14336.1,
AAV38875.1,
BAD97086.1,
EAW50990.1,
EAW50987.1
Gene_ORFName:
hCG_1985580
Ensembl_TRS:
ENST00000264933,
ENST00000505221,
ENST00000507528,
ENST00000614778,
ENST00000618970
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000423815,
ENSP00000422085,
ENSP00000264933,
ENSP00000485024,
ENSP00000482332
RefSeq:
NP_037364.1,
NP_001254486.1,
NP_001254487.1,
NP_001254488.1,
NP_001254485.1
|
| Others |
UniRef100:
UniRef100_A0A087WZ38,
UniRef100_Q53FC3,
UniRef100_O75340,
UniRef100_A0A024QZ42
UniRef90:
UniRef90_A0A671DKL1,
UniRef90_A0A087WZ38,
UniRef90_O75340
UniRef50:
UniRef50_A0A087WZ38,
UniRef50_A0A671DP73,
UniRef50_O75340
UniGene:
Hs.50823
CCDS:
CCDS58940.1,
CCDS58941.1,
CCDS3854.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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