| Type | Description |
|---|---|
| Definition | Rho/Rac guanine nucleotide exchange factor 2 |
| Date | Results | Publications |
|---|---|---|
| 2013-09-21 12:39:00 | Data indicate that TNF-alpha stimulates Rac, ADAM17/TACE, and RhoA through the guanine nucleotide exchange factor (GEF)-H1. | 23389627 |
| 2010-09-13 12:08:00 | Data indicate that GEF-H1 is a target and functional effector of TGF-beta by orchestrating Rho signaling to regulate gene expression and cell migration. | 20089843 |
| 2010-06-28 11:07:00 | ERK/GEF-H1/Rho/ROK/pMLC pathway could be a central mechanism whereby electrogenic transmembrane transport processes control myosin phosphorylation and regulate paracellular transport in the tubular epithelium. | 20237148 |
| 2010-01-21 00:00:00 | the ERK/GEF-H1/Rho/Rho kinase/phospho-MLC pathway is the mechanism mediating TNF-alpha-induced elevation of tubular epithelial permeability, which in turn might contribute to kidney injury | 19261619 |
| Type | IDs |
|---|---|
| Synonymous | GEF-H1 |
| Gene |
UniProtKB-ID:
ARHG2_PIG,
F1RLP5_PIG,
A0A287B9P3_PIG,
A0A287ATI0_PIG
UniprotKB:
B2DCZ9,
F1RLP5,
A0A287B9P3,
A0A287ATI0
UniParc:
UPI0003AECEDA,
UPI00017F0B11,
UPI000172CF63,
UPI0003AEA3F5
EMBL:
AEMK02000022,
AB364503
Ensembl:
ENSSSCG00000006502
KO:
ssc:100145887
|
| Nucleutide sequences |
EMBL-CDS:
BAG24505.1
Ensembl_TRS:
ENSSSCT00000007121,
ENSSSCT00000066112,
ENSSSCT00000047021
|
| Protein sequencees |
Ensembl_PRO:
ENSSSCP00000006929,
ENSSSCP00000052807,
ENSSSCP00000047172
RefSeq:
NP_001121935.1,
XP_020944129.1,
XP_005663337.1,
XP_020944130.1,
XP_020944128.1,
XP_013852419.1,
XP_020944131.1,
XP_013852418.1,
XP_005663339.1,
XP_005663336.1,
XP_020944132.1,
XP_013852420.1,
XP_005663334.1,
XP_005663343.1,
XP_020944127.1,
XP_005663341.1,
XP_013852417.1,
XP_005663338.1
|
| Others |
UniRef100:
UniRef100_B2DCZ9,
UniRef100_F1RLP5,
UniRef100_A0A480WJA0,
UniRef100_A0A287B9P3
UniRef90:
UniRef90_F1RLP5,
UniRef90_F7DTM0,
UniRef90_B2DCZ9
UniRef50:
UniRef50_F1RLP5,
UniRef50_F7BYT9,
UniRef50_B2DCZ9
UniGene:
Ssc.8984
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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