| Type | Description |
|---|---|
| Definition | killin, p53 regulated DNA replication inhibitor |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 12:17:00 | MiR-744-3p regulates the proliferation and differentiation of keratinocytes through targeting KLLN in psoriasis | 30664260 |
| 2018-07-14 10:08:00 | Data suggest that low levels of PTEN and KLLN are associated with both sporadic papillary thyroid carcinoma and multi-nodular goiter (as compared to control subjects); however, PTEN and KLLN should not be considered as circulating biomarkers for differential diagnosis between malignancy and benignity in indeterminate thyroid nodules. (PTEN = phosphatase and tensin homolog; KLLN = DNA replication inhibitor killin) | 28755140 |
| 2017-07-08 10:21:00 | The results suggest a critical role for KLLN as a potential regulator of pericentric heterochromatin formation, genomic stability and gene expression. | 26673699 |
| 2017-03-11 12:38:00 | overexpression of microRNA-224 enhanced the proliferation abilities of HO8910 and knockdown of microRNA-224 suppressed the proliferation abilities of HO8910PM by KLLN-cyclin A pathway. | 27663866 |
| 2016-05-07 10:23:00 | Germline promoter hypermethylation of KLLN is associated with particular malignant and benign Cowden syndrome features, which is dependent on the PTEN mutation status. | 25669429 |
| Type | IDs |
|---|---|
| Synonymous | CWS4, KILLIN |
| Gene |
UniProtKB-ID:
KILIN_HUMAN
UniprotKB:
B2CW77
UniParc:
UPI0000197BAB
EMBL:
AC063965,
EU552092
Ensembl:
ENSG00000283059,
ENSG00000227268
KO:
hsa:100144748
|
| Nucleutide sequences |
EMBL-CDS:
ACB45456.1
Ensembl_TRS:
ENST00000644082,
ENST00000635224,
ENST00000445946
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000392204,
ENSP00000489239,
ENSP00000495113
RefSeq:
NP_001119521.1
|
| Others |
UniRef100:
UniRef100_B2CW77
UniRef90:
UniRef90_B2CW77
UniRef50:
UniRef50_B2CW77
UniGene:
Hs.559820
CCDS:
CCDS44454.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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