| Type | Description |
|---|---|
| Definition | histone deacetylase 5 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:17:00 | Whole Exome Sequencing Identifies APCDD1 and HDAC5 Genes as Potentially Cancer Predisposing in Familial Colorectal Cancer. | 33673279 |
| 2020-11-21 13:20:00 | HDAC4 and 5 repression of TBX5 is relieved by protein kinase D1. | 31784580 |
| 2020-06-20 11:34:00 | This study reveals that HDAC5 regulated by C-MYC is essential for SOX9 deacetylation and nuclear localisation, which is critical for tamoxifen resistance. These results indicate a potential therapy strategy for ER(+) breast cancer by targeting C-MYC/HDAC5/SOX9 axis. | 31690832 |
| 2019-08-17 10:53:00 | HDAC5 overexpression in urothelial carcinoma cell lines decreases cell proliferation but can promote epithelial-to-mesenchymal transition. | 31052182 |
| 2019-07-20 11:02:00 | It identified BMAL1 as a cAMP-responsive coactivator of HDAC5 to regulate hepatic gluconeogenesis | 29508277 |
| Type | IDs |
|---|---|
| Synonymous | HD5, NY-CO-9 |
| Gene |
UniProtKB-ID:
HDAC5_HUMAN
UniprotKB:
Q9UQL6
UniParc:
UPI0000508BBA,
UPI0000161FB3,
UPI0000201355
EMBL:
AC023855,
BX458255,
AF039691,
BC013140,
BK000028,
BC051824,
AF132608,
AB011172
Ensembl:
ENSG00000108840
KO:
hsa:10014
|
| Nucleutide sequences |
EMBL-CDS:
BAA25526.2,
AAH13140.1,
AAC18040.1,
AAD29047.1,
DAA00017.1,
AAH51824.1
Ensembl_TRS:
ENST00000586802,
ENST00000225983,
ENST00000336057
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000468004,
ENSP00000225983,
ENSP00000337290
RefSeq:
XP_016879482.1,
NP_001369322.1,
NP_001015053.1,
NP_005465.2,
XP_016879481.1,
XP_011522452.1,
XP_011522451.1,
XP_016879479.1,
XP_005256962.1,
XP_016879480.1,
XP_016879478.1,
XP_016879485.1,
XP_016879477.1
|
| Others |
UniRef100:
UniRef100_Q9UQL6
UniRef90:
UniRef90_Q9UQL6
UniRef50:
UniRef50_Q9UQL6
UniGene:
Hs.438782
CCDS:
CCDS32663.1,
CCDS45696.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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