| Type | Description |
|---|---|
| Definition | TEN1 subunit of CST complex |
| Date | Results | Publications |
|---|---|---|
| 2020-07-04 11:28:00 | This work provides a blueprint to pinpoint the possible consequences of pathogenic mutations in the CST complex subunit TEN1. | 31028137 |
| 2020-02-29 11:59:00 | CST functions in two distinct aspects of genome-wide DNA replication, namely, origin licensing and replisome assembly. CST interacts with additional replisome components, MCM and AND-1. | 30979824 |
| 2019-12-07 11:33:00 | The CST complex (CTC1-STN1-TEN1) maintains genome integrity through resolution of G4 structures both ahead of the replication fork and on the lagging strand template | 30976812 |
| 2019-02-02 12:26:00 | Studies indicate telomere-binding proteins CTC1-STN1-TEN1 (CST) dysfunction and mutation is associated with several genetic diseases and cancers [Review]. | 29293451 |
| 2018-12-22 11:33:00 | CTC1-STN1 terminates TERT while STN1-TEN1 enables C-strand synthesis during telomere replication in colon cancer cells. | 30026550 |
| Type | IDs |
|---|---|
| Synonymous | C17orf106 |
| Gene |
UniProtKB-ID:
TEN1L_HUMAN
UniprotKB:
Q86WV5
UniParc:
UPI00005A8BEF
EMBL:
AC040980,
AK097104,
BM558420,
BC047782,
BX647274
Ensembl:
ENSG00000257949
KO:
hsa:100134934
|
| Nucleutide sequences |
EMBL-CDS:
AAH47782.1
Ensembl_TRS:
ENST00000397640
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000380762
RefSeq:
NP_001106795.2
|
| Others |
UniRef100:
UniRef100_Q86WV5
UniRef90:
UniRef90_Q86WV5
UniRef50:
UniRef50_Q86WV5
UniGene:
Hs.593566
CCDS:
CCDS45780.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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