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100132285 KIR2DS2

100132285

KIR2DS2

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2

研究结论

Date Results Publications
2020-05-30 11:51:00 The combination KIR2DS2/KIR2DL2/C1 correlated with severe Alzheimer's Disease status and an increased susceptibility to HHV-6A infection. 30689576
2019-09-28 12:29:00 matching of KIR2DL1, 2DS1, and 2DS2 in donors with their HLA-C ligands in recipients is associated with increased GvHD, and holds potential for selection of HSCT donors. 29549293
2019-06-08 10:40:00 The multivariate analysis revealed that the lack of KIR2DS2 (p = 0.035), the presence of KIR2DL3 (p = 0.075), and the presence of KIR2DL2HLA-C1 (p = 0.044) were risk factors for posttransplant cytomegalovirus infection. 30696053
2017-07-29 12:51:00 Genotypes missing these two inhibitory KIR-HLA combinations in addition to missing activating KIRs 2DS2 and 2DS3 were more common in Vogt-Koyanagi-Harada disease (OR = 1.90, P = 0.002). 27490240
2017-05-27 10:08:00 KIR2DS2/HLA-C1 may correlate with Hashimoto thyroiditis in a Chinese population. 27042744

名称对应

Type IDs
Synonymous 183ActI, CD158J, CD158b, KIR-2DS2, NKAT-5, NKAT5, cl-49
Gene
UniProtKB-ID: KI2S2_HUMAN, Q14950_HUMAN, A0A0G2JPR7_HUMAN, O43755_HUMAN, A0A1W2PSB7_HUMAN, K7R1S5_HUMAN, Q32MZ1_HUMAN, O75579_HUMAN
UniprotKB: P43631, Q14950, A0A0G2JPR7, O43755, A0A1W2PSB7, K7R1S5, Q32MZ1, O75579
UniParc: UPI0000071C17, UPI00000739D0, UPI00021AED77, UPI000006E41F, UPI0000001314, UPI00021AED78, UPI00005DC72E
EMBL: AJ002104, MN167506, L41347, KP420441, AL133414, AF074087, LS974081, BC108917, MN167528, MN167515, X89893, MN167517, U24079, JX008030, CU464060, AY366243, MN167520, L76668, GU182349, MN167510, CU467816, KP420440, KP420444
Ensembl: ENSG00000278300, ENSG00000284033, ENSG00000284511, ENSG00000277885, ENSG00000275452, ENSG00000275583, ENSG00000276139
KO: hsa:100132285
Nucleutide sequences
EMBL-CDS: AAR16201.1, CAA61983.1, AAC50338.1, AAA65225.1, AAB36596.1, SSB88430.1, CAA05184.1, QKY12239.1, QKY12277.1, QKY12395.1, QKY12213.1, QKY12294.1, AFV74762.1, AJI81012.1, AJI81029.1, QKY12325.1, AJI81000.1, AAI08918.1, AAC26790.1
Ensembl_TRS: ENST00000616541, ENST00000616472, ENST00000610441, ENST00000617284, ENST00000638349, ENST00000646291, ENST00000613952, ENST00000644423, ENST00000638490, ENST00000622343, ENST00000616523, ENST00000639105, ENST00000614622, ENST00000642421, ENST00000639275, ENST00000645082, ENST00000642658, ENST00000640850, ENST00000640647, ENST00000647064
Protein sequencees
Ensembl_PRO: ENSP00000484281, ENSP00000482637, ENSP00000478014, ENSP00000484771, ENSP00000492863, ENSP00000493941, ENSP00000494593, ENSP00000483805, ENSP00000492615, ENSP00000477585, ENSP00000495382, ENSP00000491429, ENSP00000491269, ENSP00000481218, ENSP00000484133, ENSP00000493506, ENSP00000492611, ENSP00000492774, ENSP00000494525, ENSP00000494057
RefSeq: XP_016885764.1, NP_036444.1, NP_001278624.1, NP_001278629.1, NP_001278630.1, NP_001278625.1
Others
UniRef100: UniRef100_P43631, UniRef100_A0A1W2PSB7, UniRef100_O43755, UniRef100_Q32MZ1, UniRef100_A0A0G2JPR7, UniRef100_Q14950, UniRef100_O75579
UniRef90: UniRef90_Q14953, UniRef90_O75579, UniRef90_Q14950, UniRef90_Q32MZ1, UniRef90_P43628
UniRef50: UniRef50_P43626, UniRef50_P43628, UniRef50_O75579, UniRef50_Q14950
UniGene: Hs.512572, Hs.731378

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