| Type | Description |
|---|---|
| Definition | SCO2 cytochrome c oxidase assembly protein |
| Date | Results | Publications |
|---|---|---|
| 2018-05-19 11:55:00 | Sco2 deficient mice develop increased adiposity, liver steatosis, and insulin resistance. | 28428045 |
| 2011-12-31 10:40:00 | Data suggest that physical exercise attenuates age-related changes in mitochondrial COX biogenesis and p53 activity targeting SCO2 and mitochondria, and thereby induces antisenescent and protective effects in cardiac muscle. | 21750704 |
| 2011-03-26 11:26:00 | Results describe the tissue distribution of SCO1 and SCO2 in mouse and human tissues. | 20864674 |
| 2010-03-15 11:37:00 | To understand the biological role of SCO2, mice harboring both a Sco2 knock-out (KO) allele and a Sco2 knock-in (KI) E129K allele, corresponding to the common E140K mutation in humans, were studied. | 19837698 |
| 2010-01-21 00:00:00 | findings show that p53 modulates the balance between the utilization of respiratory and glycolytic pathways; identifed Synthesis of Cytochrome c Oxidase 2 (SCO2) as the downstream mediator of this effect | 16728594 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
SCO2_MOUSE
UniprotKB:
Q8VCL2
UniParc:
UPI0000028935
EMBL:
BC019554
Ensembl:
ENSMUSG00000091780
KO:
mmu:100126824
|
| Nucleutide sequences |
EMBL-CDS:
AAH19554.1
Ensembl_TRS:
ENSMUST00000228977,
ENSMUST00000167643
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000131943,
ENSMUSP00000155150
RefSeq:
NP_001104758.1
|
| Others |
UniRef100:
UniRef100_Q8VCL2
UniRef90:
UniRef90_Q8VCL2
UniRef50:
UniRef50_Q8VCL2
UniGene:
Mm.287977
CCDS:
CCDS49701.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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