| Type | Description |
|---|---|
| Definition | gene amplified in esophageal cancer 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-11-09 10:10:00 | GAEC1 affects mitochondrial respiration by reducing the coupling efficiency in colon adenocarcinoma of the advanced stages (stage III with lymph node metastases). GAEC1 is involved in the interaction between pAkt, FOXO3, and MMP9 in colon adenocarcinoma and may drive the cancer progression through the positive feedback regulation of the Akt/FOXO3/MMP9 signaling pathway. | 30825264 |
| 2018-09-29 12:06:00 | The high expression of GAEC1 mRNA/protein as well as its correlation with multiple clinicopathological characteristics in patients with colorectal carcinoma strongly suggests that GAEC1 is a key regulator in the initiation of colorectal carcinogenesis. | 29337242 |
| 2018-09-01 10:43:00 | GAEC1 mutation affects GAEC1 expression and is associated with poorer clinical outcomes in colorectal cancer | 29555101 |
| 2018-06-09 11:48:00 | a xenotransplantation model showed that stable knockdown of GAEC1 using shRNA constructs in colon cancer cells fully suppressed xenograft tumour growth in mice. Collectively, the expression analysis, in vitro and in vivo data indicated that GAEC1 is differentially expressed in cancer cells and act as an oncogene in colon cancer progression | 28764863 |
| 2013-12-14 10:47:00 | GAEC1 regulates the expression of CAPN10 and TNRC6C in esophageal squamous cell carcinoma. | 23687414 |
| Type | IDs |
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