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10008 KCNE3

10008

KCNE3

potassium voltage-gated channel subfamily E regulatory subunit 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition potassium voltage-gated channel subfamily E regulatory subunit 3

研究结论

Date Results Publications
2018-06-02 11:20:00 Regulation of human cardiac potassium channels by full-length KCNE3 and KCNE4 has been reported. 27922120
2018-01-27 10:43:00 Structural, computational, biochemical, and electrophysiological studies lead to an atomically explicit integrative structural model of the KCNE3-KCNQ1 complex that explains how KCNE3 induces the constitutive activation of KCNQ1 channel activity, a crucial component in K(+) recycling. 27626070
2017-08-26 10:42:00 Reported here are previously undiscovered protein-coding regions in exon 1 of hKCNE3 and hKCNE4 that extend their encoded extracellular domains by 44 and 51 residues, which yields full-length proteins of 147 and 221 residues, respectively. 27162025
2016-12-17 10:46:00 Based on current evidence from published studies, neither of the two variants from KCNE was significantly associated with the risk of Meniere's disease--{REVIEW} 26890422
2016-08-13 10:16:00 Data show that voltage-gated potassium channel KCNE3 directly affects the S4 movement in potassium channel KCNQ1. 26668384

名称对应

Type IDs
Synonymous BRGDA6, HOKPP, HYPP, MiRP2
Gene
UniProtKB-ID: KCNE3_HUMAN, Q6IAE6_HUMAN
UniprotKB: Q9Y6H6, Q6IAE6
UniParc: UPI000012F15C
EMBL: CR457209, BC032235, CH471076, AF076531, CR936625, AK311876, AF302494, DQ784805, BC110612, BC113743
Ensembl: ENSG00000175538
KO: hsa:10008
Nucleutide sequences
EMBL-CDS: AAG16255.1, AAD28089.1, AAI10613.1, BAG34817.1, AAI13744.1, EAW74938.1, CAI56768.1, ABQ01240.1, CAG33490.1
Gene_ORFName: hCG_27327
Ensembl_TRS: ENST00000310128, ENST00000525550
Protein sequencees
Ensembl_PRO: ENSP00000433633, ENSP00000310557
RefSeq: XP_016872538.1, XP_016872537.1, XP_016872536.1, XP_016872541.1, NP_005463.1, XP_016872540.1, XP_011543015.1
Others
UniRef100: UniRef100_Q9Y6H6
UniRef90: UniRef90_Q9Y6H6
UniRef50: UniRef50_Q9Y6H6
UniGene: Hs.523899
CCDS: CCDS8232.1

全选

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