| Type | Description |
|---|---|
| Definition | apelin receptor early endogenous ligand |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 12:20:00 | Antagonistic interaction between ELA and intrarenal renin angiotensin system in the distal nephron that appears to exert a major impact on blood pressure regulation. | 32174138 |
| 2018-05-05 10:05:00 | loss of Apela signaling impacts early Aplnr-expressing mesodermal populations. | 28854362 |
| 2017-12-30 11:12:00 | Elabela but not Apelin knockout pregnant mice exhibit preeclampsia -like symptoms, including proteinuria and elevated blood pressure due to defective placental angiogenesis. | 28663440 |
| 2017-10-14 11:08:00 | the ELABELA (ELA)-APJ signaling axis is only required for sinus venosus-derived progenitors. | 28890073 |
| 2016-09-10 10:15:00 | conclude that apela is present in the adult heart, is upregulated in post-infarction cardiac remodeling, and increases cardiac contractility in an ERK1/2-dependent manner | 26611206 |
| Type | IDs |
|---|---|
| Synonymous | Ela, Elabela, Ende, Gm10664 |
| Gene |
UniProtKB-ID:
ELA_MOUSE
UniprotKB:
P0DMC4
UniParc:
UPI0003E30FA4
EMBL:
AI930099,
AK014119,
GL456145
Ensembl:
ENSMUSG00000079042
KO:
mmu:100038489
|
| Nucleutide sequences |
Ensembl_TRS:
ENSMUST00000124790,
ENSMUST00000142822
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000140510,
ENSMUSP00000139425
RefSeq:
NP_001284483.1,
XP_011240549.1
|
| Others |
UniRef100:
UniRef100_P0DMC4
UniRef90:
UniRef90_P0DMC4
UniRef50:
UniRef50_P0DMC4
UniGene:
Mm.58847
CCDS:
CCDS80883.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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