| Type | Description |
|---|---|
| Definition | MHC class I antigen 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-11-28 13:15:00 | SLA-1 Genetic Diversity in Pigs: Extensive Analysis of Copy Number Variation, Heterozygosity, Expression, and Breed Specificity. | 31959823 |
| 2018-09-22 10:37:00 | Here, the authors report that pseudorabies virus down-regulated swine leukocyte antigen class I (SLA-I) molecules on the surface of PK-15 cells and targeted them for degradation through lysosome pathway. Viral pUL56 protein was associated with this function by inducing degradation of cellular SLA-I heavy chain (HC) in a manner that was dependent on the lysosome machinery. | 29634995 |
| 2017-10-14 12:51:00 | These results suggest that the soluble recombinant proteins may be used to prepare monoclonal antibodies to block the PD-1/PD-L1 pathway. | 28408783 |
| 2016-08-13 11:53:00 | The last 68 amino acids of TF domain in Nsp2TF of porcine reproductive and respiratory syndrome virus are critical for down-regulates the expression of SLA-1. | 26895249 |
| 2016-05-14 11:23:00 | The authors found that porcine reproductive and respiratory syndrome virus nsp1alpha was able to interact with both chains of swine leukocyte antigen class I, a requirement needed to target for proteasomal degradation. | 26491168 |
| Type | IDs |
|---|---|
| Synonymous | PD1, SLA-1a, sla- |
| Gene |
UniProtKB-ID:
A0A0A7BZR3_PIG,
A1YH77_PIG
UniprotKB:
A0A0A7BZR3,
A1YH77
UniParc:
UPI0000ED9DE5,
UPI00017EFC69
EMBL:
KF026026,
DQ992492
KO:
ssc:100037293
|
| Nucleutide sequences |
EMBL-CDS:
AHW79962.1,
ABM54831.1
|
| Protein sequencees |
RefSeq:
XP_013833010.1,
XP_020954096.1,
NP_001090900.1
|
| Others |
UniRef100:
UniRef100_A0A0A7BZR3,
UniRef100_A1YH77
UniRef90:
UniRef90_F1S1N1,
UniRef90_A0A287AQG3
UniRef50:
UniRef50_P04439-2,
UniRef50_P04439
UniGene:
Ssc.18553,
Ssc.56487
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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