| Type | Description |
|---|---|
| Definition | DnaJ heat shock protein family (Hsp40) member C3 |
| Date | Results | Publications |
|---|---|---|
| 2015-04-11 13:40:00 | Chaperone protein p58(IPK) is expressed predominantly in retinal ganglion cells (RGC), inner retinal neurons, and the photoreceptor inner segments. | 25655802 |
| 2015-03-21 10:34:00 | p58IPK is a general inhibitor of the eIF2alpha kinases in that it also interacts with GCN2. Thus forced overexpression of cytoplasmic p58 delays eIF2alpha phosphorylation, suppresses GCN2 phosphorylation and prolongs protein synthesis | 25329545 |
| 2014-05-10 12:54:00 | combined deletion of ATF6alpha and the ER cochaperone p58(IPK) resulted in synthetic embryonic lethality. | 24275136 |
| 2011-04-23 10:20:00 | Data present a working model for P58(IPK) to act together with Bip to prevent protein aggregations and promote protein foldings within ER. | 21266255 |
| 2010-09-20 11:19:00 | Coxsackievirus B3 infection induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1. | 20554776 |
| Type | IDs |
|---|---|
| Synonymous | AA408985, AU067833, Dnajc3a, Dnajc3b, Prkri, mp58, p58, p58IPK |
| Gene |
UniProtKB-ID:
DNJC3_MOUSE,
Q3UFV9_MOUSE
UniprotKB:
Q91YW3,
Q3UFV9
UniParc:
UPI0000021E0B
EMBL:
BC013766,
U28423,
AK148270
Ensembl:
ENSMUSG00000022136
KO:
mmu:100037258
|
| Nucleutide sequences |
EMBL-CDS:
AAH13766.1,
AAC52592.1,
BAE28450.1
Ensembl_TRS:
ENSMUST00000022734
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000022734
RefSeq:
NP_032955.2
|
| Others |
UniRef100:
UniRef100_Q91YW3
UniRef90:
UniRef90_Q13217
UniRef50:
UniRef50_Q13217
UniGene:
Mm.12616
CCDS:
CCDS37012.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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