| Type | Description |
|---|---|
| Definition | fukutin |
| Date | Results | Publications |
|---|---|---|
| 2012-03-10 10:25:00 | Fukutin and FKRP have functions that affect ocular development in zebrafish independently of dystroglycan. | 21926082 |
| 2011-08-20 10:09:00 | Muscle pathology in embryos lacking Fukutin or FKRP is different from loss of dystroglycan; knockdown of Fukutin or FKRP leads to a notochord defect and a perturbation of laminin expression before muscle degeneration. | 21317159 |
| Type | IDs |
|---|---|
| Synonymous | fcmd, im:7163166, zgc:162828 |
| Gene |
UniProtKB-ID:
A3KP10_DANRE
UniprotKB:
A3KP10
UniParc:
UPI0000F3B902
EMBL:
BC134110
KO:
dre:100006345
|
| Nucleutide sequences |
EMBL-CDS:
AAI34111.1
|
| Protein sequencees |
RefSeq:
NP_001036159.2,
XP_021331643.1
|
| Others |
UniRef100:
UniRef100_A3KP10
UniRef90:
UniRef90_Q0PIP6
UniRef50:
UniRef50_A0A286XHE9
UniGene:
Dr.84293
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30232282 |
JCI Insight Peter R Serafini , Michael J Feyder , Rylie M Hightower , Daniela Garcia-Perez , Natássia M Vieira , Angela Lek , Devin E Gibbs , Omar Moukha-Chafiq , Corinne E Augelli-Szafran , Genri Kawahara , Jeffrey J Widrick , Louis M Kunkel , Matthew S Alexander |
2018-09-20 | - |
| 27189481 |
Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. BMC Genomics Jeremy Pasquier , Cédric Cabau , Thaovi Nguyen , Elodie Jouanno , Dany Severac , Ingo Braasch , Laurent Journot , Pierre Pontarotti , Christophe Klopp , John H Postlethwait , Yann Guiguen , Julien Bobe |
2016-05-18 | - |
| 25583992 |
Cardiac transcriptome and dilated cardiomyopathy genes in zebrafish. Circ Cardiovasc Genet Yu-Huan Shih , Yuji Zhang , Yonghe Ding , Christian A Ross , Hu Li , Timothy M Olson , Xiaolei Xu |
2015-04-01 |
smyhc3,
si:ch211-24n20.3,
ttnb,
fktn,
pln,
ankrd1a,
nppb,
myh7ba,
lmna,
desma,
psen1,
cryaba,
vmhc,
pcna,
ttna,
nppa,
smyhc1,
taz,
dspb,
dspa,
tpm4b,
sgcd,
ldb3b,
myhc4,
myl1,
si:ch73-187m15.4,
tmpoa,
tnnc1a,
tnnt2c,
myh6,
ilk,
dnajc19,
sdha,
tpm1,
atp2a2a,
tnni2a.2,
tnni2a.3,
acta1b,
actc1a,
tnnc1b,
tnni1al,
tnni1d,
cryabb,
tnni2b.2,
bag3,
fhl2a,
cav3,
zgc:101560,
csrp3,
fhl2b,
tnni2a.1,
tnni1b,
tnni2a.4,
rbm20,
lamp2,
nebl,
eya4,
tnni2b.1,
acta1a,
vcla,
slc8a1a,
tmpob,
zgc:112242,
pdlim3a,
tcap,
mybpc3,
tnni1a,
syne2b,
dsc2l,
myh7bb,
abcc9,
pdlim3b,
si:dkey-206m15.8,
ankrd1b,
lama4,
scn12ab,
syne1b,
pkp2,
ryr2b,
slc8a2a,
syne1a,
mypn,
nexn,
psen2,
tnnt2a,
tnnc2,
actc1b,
mylz3,
actn2b,
cmlc1,
gatad1,
tnni1c,
desmb,
vmhcl,
ldb3a,
scn12aa,
myl6,
dmd
|
| 22522421 |
Mutations in ISPD cause Walker-Warburg syndrome and defective glycosylation of α-dystroglycan. Nat. Genet. Tony Roscioli , Erik-Jan Kamsteeg , Karen Buysse , Isabelle Maystadt , Jeroen van Reeuwijk , Christa van den Elzen , Ellen van Beusekom , Moniek Riemersma , Rolph Pfundt , Lisenka E L M Vissers , Margit Schraders , Umut Altunoglu , Michael F Buckley , Han G Brunner , Bernard Grisart , Huiqing Zhou , Joris A Veltman , Christian Gilissen , Grazia M S Mancini , Paul Delrée , Michèl A Willemsen , Danijela PetkoviÄ Ramadža , David Chitayat , Christopher Bennett , Eamonn Sheridan , Els A J Peeters , Gita M B Tan-Sindhunata , Christine E de Die-Smulders , Koenraad Devriendt , Hülya Kayserili , Osama Abd El-Fattah El-Hashash , Derek L Stemple , Dirk J Lefeber , Yung-Yao Lin , Hans van Bokhoven |
2012-05-01 | - |
| 21926082 |
Abnormal vascular development in zebrafish models for fukutin and FKRP deficiency. Hum. Mol. Genet. Alasdair J Wood , Juliane S Müller , Catherine D Jepson , Steve H Laval , Hanns Lochmüller , Kate Bushby , Rita Barresi , Volker Straub |
2011-12-15 | - |
| 21317159 |
Zebrafish Fukutin family proteins link the unfolded protein response with dystroglycanopathies. Hum. Mol. Genet. Yung-Yao Lin , Richard J White , Silvia Torelli , Sebahattin Cirak , Francesco Muntoni , Derek L Stemple |
2011-05-01 | - |
| 18632251 |
Genes required for functional glycosylation of dystroglycan are conserved in zebrafish. Genomics Christopher J Moore , Huey Tse Goh , Jane E Hewitt |
2008-09-01 |
fktn,
dag1,
large,
gyltl1b,
pomt2,
pomt1,
fkrp,
pomgnt1
|
| 18973681 |
BMC Genomics Xavier Argout , Olivier Fouet , Patrick Wincker , Karina Gramacho , Thierry Legavre , Xavier Sabau , Ange Marie Risterucci , Corinne Da Silva , Julio Cascardo , Mathilde Allegre , David Kuhn , Joseph Verica , Brigitte Courtois , Gaston Loor , Regis Babin , Olivier Sounigo , Michel Ducamp , Mark J Guiltinan , Manuel Ruiz , Laurence Alemanno , Regina Machado , Wilberth Phillips , Ray Schnell , Martin Gilmour , Eric Rosenquist , David Butler , Siela Maximova , Claire Lanaud |
2008-01-01 |
LOC4341419,
LOC9267109,
fktn,
ifngr1,
LOC100536294,
epcam,
yif1b,
ythdc1,
gcga,
nsun4,
si:ch73-173h19.3,
MIR137,
MIR9857,
MIR9859,
MIR9787,
MIR9784-2,
MIR9800,
MIR9798
|
| 17374169 |
Zebrafish orthologs of human muscular dystrophy genes. BMC Genomics Leta S Steffen , Jeffrey R Guyon , Emily D Vogel , Rosanna Beltre , Timothy J Pusack , Yi Zhou , Leonard I Zon , Louis M Kunkel |
2007-01-01 |
slc1a5,
fsd1l,
itga7,
fktn,
flnca,
lama2,
lmna,
desma,
ttna,
sgcd,
col1a1b,
mtfr1l,
sepn1,
sgce,
pabpn1,
sgcg,
large,
capn3a,
cav3,
tcap,
col6a3,
sgca,
emd,
sgcb,
flna,
trim32,
strn4,
col6a2,
col6a1,
pomt1,
flncb,
fkrp,
pomgnt1,
dmd
|
| 12618376 |
Genome Res. Jane Lo , Sorcheng Lee , Min Xu , Feng Liu , Hua Ruan , Alvin Eun , Yawen He , Weiping Ma , Weefuen Wang , Zilong Wen , Jinrong Peng |
2003-03-01 |
slc12a8,
sema5bb,
tmprss3a,
si:dkey-22o12.2,
rab32b,
si:ch211-166a6.5,
mettl24,
rragcb,
gpn3,
abl1,
glula,
map6a,
si:dkey-11p10.10,
eml6,
golim4a,
htr2cl1,
si:ch211-241d21.5,
iars2,
znf207b,
si:dkeyp-69e1.8,
fbxo30a,
rab22a,
calb1,
fam160a2,
ponzr10,
mtg2,
hectd1,
slc1a5,
rasa1a,
olfml2a,
lmod1a,
lenep,
pimr168,
si:dkey-49o11.1,
LOC100002756,
nkain4,
cdc42ep4b,
si:dkey-105e17.1,
tmem150c,
tcirg1a,
ppp1cb,
lrch4,
abhd17ab,
plekhb2,
aknad1,
colgalt2,
pmch,
anks1ab,
si:ch211-204d2.4,
si:ch211-226m16.2,
sgpp1,
trim2a,
znf516,
zeb2a,
zgc:112265,
p2ry1,
adamts12,
si:ch211-198n5.11,
med13a,
ddb2,
tbx5b,
cd28,
kcnt1,
si:dkey-61l1.4,
cep350,
tmc8,
slc35a1,
atp6ap1a,
fsd1l,
cyp24a1,
si:ch211-243a15.1,
c1ql2,
ar,
dnmbp,
calhm1,
mybl2a,
ice2,
dnal4b,
slc5a7a,
cpo,
grin1b,
cgnb,
ehmt1a,
tuft1b,
arrdc1a,
znf687b,
sobpb,
si:dkey-266f7.5,
itga7,
si:dkeyp-53d3.6,
fktn,
whsc1l1,
senp7b,
alx4a,
slc2a5,
atf2,
si:ch73-177h5.3,
prkcba,
ankrd55
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员