| Type | Description |
|---|---|
| Definition | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A, a |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 11:23:00 | DYRK1A plays an essential role in angiogenesis and in maintenance of the developing cerebral vasculature via regulation of calcium signaling. | 31043432 |
| 2019-12-21 11:54:00 | The dyrk1aa KO zebrafish showed impaired social preference compared with WT in the social behavior test. | 31058587 |
| 2019-07-06 12:22:00 | overexpression of DYRK1A, a candidate gene of Down's syndrome, impairs PGCs development during early embryogenesis by altering key factors in embryos. | 29127398 |
| Type | IDs |
|---|---|
| Synonymous | dyrk1a, im:6962097, zgc:158359 |
| Gene |
UniProtKB-ID:
A1L1U2_DANRE
UniprotKB:
A1L1U2
UniParc:
UPI0000ECF182
EMBL:
BC129212
KO:
dre:100005019
|
| Nucleutide sequences |
EMBL-CDS:
AAI29213.1
|
| Protein sequencees |
RefSeq:
XP_009303309.2,
NP_001334668.1,
NP_001074158.1
|
| Others |
UniRef100:
UniRef100_A1L1U2
UniRef90:
UniRef90_A1L1U2
UniRef50:
UniRef50_Q13627
UniGene:
Dr.20592
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 31058587 |
Zebrafish Morteza Aslanzadeh , Krishan Ariyasiri , Oc-Hee Kim , Tae-Ik Choi , Jae-Hoon Lim , Hyung-Goo Kim , Robert Gerlai , Cheol-Hee Kim |
2019-06-01 | - |
| 31043432 |
Vascular defects of DYRK1A knockouts are ameliorated by modulating calcium signaling in zebrafish. Dis Model Mech Hyun-Ju Cho , Jae-Geun Lee , Jong-Hwan Kim , Seon-Young Kim , Yang Hoon Huh , Hyo-Jeong Kim , Kyu-Sun Lee , Kweon Yu , Jeong-Soo Lee |
2019-05-23 | - |
| 29127398 |
Sci Rep Yanyan Liu , Ziyuan Lin , Mingfeng Liu , He Wang , Huaqin Sun |
2017-11-10 | - |
| 28252024 |
Evolution of complexity in the zebrafish synapse proteome. Nat Commun Ãlex Bayés , Mark O Collins , Rita Reig-Viader , Gemma Gou , David Goulding , Abril Izquierdo , Jyoti S Choudhary , Richard D Emes , Seth G N Grant |
2017-03-02 | - |
| 29021890 |
Zebrafish knockout of Down syndrome gene, DYRK1A, shows social impairments relevant to autism. Mol Autism Oc-Hee Kim , Hyun-Ju Cho , Enna Han , Ted Inpyo Hong , Krishan Ariyasiri , Jung-Hwa Choi , Kyu-Seok Hwang , Yun-Mi Jeong , Se-Yeol Yang , Kweon Yu , Doo-Sang Park , Hyun-Woo Oh , Erica E Davis , Charles E Schwartz , Jeong-Soo Lee , Hyung-Goo Kim , Cheol-Hee Kim |
2017-01-01 | - |
| 26469318 |
RFX transcription factors are essential for hearing in mice. Nat Commun Ran Elkon , Beatrice Milon , Laura Morrison , Manan Shah , Sarath Vijayakumar , Manoj Racherla , Carmen C Leitch , Lorna Silipino , Shadan Hadi , Michèle Weiss-Gayet , Emmanuèle Barras , Christoph D Schmid , Aouatef Ait-Lounis , Ashley Barnes , Yang Song , David J Eisenman , Efrat Eliyahu , Gregory I Frolenkov , Scott E Strome , Bénédicte Durand , Norann A Zaghloul , Sherri M Jones , Walter Reith , Ronna Hertzano |
2015-10-15 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21187971 |
Tiling histone H3 lysine 4 and 27 methylation in zebrafish using high-density microarrays. PLoS ONE Leif C Lindeman , Andrew H Reiner , Sinnakaruppan Mathavan , Peter Aleström , Philippe Collas |
2010-01-01 |
dyrk1aa,
sim2,
tram1,
pou5f3,
otx1b,
sox3,
foxa3,
nnr,
hyou1,
hlcs,
sox2,
pnpla6,
hist2h2l,
tiprl,
zgc:76872,
zpr1,
wfikkn1,
dscr3,
erg,
eif5b,
vps11,
ift46,
actb1,
actb2,
gata6,
klf17,
ripply3,
tert
|
| 16109975 |
The zebrafish gene map defines ancestral vertebrate chromosomes. Genome Res. Ian G Woods , Catherine Wilson , Brian Friedlander , Patricia Chang , Daengnoy K Reyes , Rebecca Nix , Peter D Kelly , Felicia Chu , John H Postlethwait , William S Talbot |
2005-09-01 |
fgfr4,
pik3r3b,
trpv6,
poldip2,
dnase2,
rtf1,
ube2g1b,
ppp1r14bb,
pvalb3,
znf207b,
olig1,
sufu,
msi2a,
ppp4ca,
ppp1cb,
socs9,
nhp2,
kat8,
laptm4a,
fsta,
mthfd2,
mob1a,
dyrk1aa,
greb1l,
fn1a,
aldh9a1a.1,
cpt2,
sh3gl1a,
vps18,
arrdc1a,
sv2bb,
idh1,
sb:cb37,
tle3b,
erbb4a,
ap1g2,
parp2,
hbl3,
dhx37,
pcsk7,
rmdn3,
gtf3ab,
kif3b,
npl,
sall1b,
pard6ga,
arfgef1,
gdf5,
cog1,
casr,
slc25a28,
urb1,
ndufv3,
trip11,
casq2,
mpz,
rps9,
vars,
spry4,
ube2ia,
dlg1,
sim2,
blzf1,
copb2,
sec22ba,
tnfsf10l,
ednraa,
pklr,
vcana,
ywhag1,
jag1a,
jag2b,
jag1b,
vim,
tfap2a,
prps1a,
atic,
cyp1a,
ckbb,
psap,
gbx1,
ptk2ab,
meis1b,
mkrn2,
rbp5,
crabp2a,
ccna2,
hdac1,
csnk1a1,
mak16,
actl6a,
dtl,
stil,
pole2,
slc25a5,
cct7,
cct3,
smc4,
kif11
|
| 12477932 |
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. Robert L Strausberg , Elise A Feingold , Lynette H Grouse , Jeffery G Derge , Richard D Klausner , Francis S Collins , Lukas Wagner , Carolyn M Shenmen , Gregory D Schuler , Stephen F Altschul , Barry Zeeberg , Kenneth H Buetow , Carl F Schaefer , Narayan K Bhat , Ralph F Hopkins , Heather Jordan , Troy Moore , Steve I Max , Jun Wang , Florence Hsieh , Luda Diatchenko , Kate Marusina , Andrew A Farmer , Gerald M Rubin , Ling Hong , Mark Stapleton , M Bento Soares , Maria F Bonaldo , Tom L Casavant , Todd E Scheetz , Michael J Brownstein , Ted B Usdin , Shiraki Toshiyuki , Piero Carninci , Christa Prange , Sam S Raha , Naomi A Loquellano , Garrick J Peters , Rick D Abramson , Sara J Mullahy , Stephanie A Bosak , Paul J McEwan , Kevin J McKernan , Joel A Malek , Preethi H Gunaratne , Stephen Richards , Kim C Worley , Sarah Hale , Angela M Garcia , Laura J Gay , Stephen W Hulyk , Debbie K Villalon , Donna M Muzny , Erica J Sodergren , Xiuhua Lu , Richard A Gibbs , Jessica Fahey , Erin Helton , Mark Ketteman , Anuradha Madan , Stephanie Rodrigues , Amy Sanchez , Michelle Whiting , Anup Madan , Alice C Young , Yuriy Shevchenko , Gerard G Bouffard , Robert W Blakesley , Jeffrey W Touchman , Eric D Green , Mark C Dickson , Alex C Rodriguez , Jane Grimwood , Jeremy Schmutz , Richard M Myers , Yaron S N Butterfield , Martin I Krzywinski , Ursula Skalska , Duane E Smailus , Angelique Schnerch , Jacqueline E Schein , Steven J M Jones , Marco A Marra , Mammalian Gene Collection Program Team |
2002-12-24 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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| 排名 | 研究人员 | 文献 |
|---|---|---|
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