Molecular cloning, expression, and functional characterization of novel mouse sulfotransferases.
Biochem. Biophys. Res. Commun.1998 Jun 29;247(3):681-6
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摘要
Nucleotide sequences of two mouse cDNAs encoding new sulfotransferase enzymes were determined. Analysis of the deduced amino acid sequences revealed that one represents a novel member of the phenol sulfotransferase family and the other is highly homologous to human SULT2B1 hydroxysteroid sulfotransferases. The recombinant enzymes, transiently expressed in COS-7 cells, were characterized with respect to their substrate specificity using a variety of substrates for different types of sulfotransferases. The tissue-specific expression of these two new mouse sulfotransferases was examined by Northern blot analysis.
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基因功能
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原始数据
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文献解读
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